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View Structure Prediction Details

Protein: FASTKD2
Organism: Homo sapiens
Length: 710 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FASTKD2.

Description E-value Query
Range
Subject
Range
FAKD2_PONAB - FAST kinase domain-containing protein 2, mitochondrial OS=Pongo abelii GN=FASTKD2 PE=2 SV=1
K0971_PONPY, FAK... - (Q5R776) Protein KIAA0971 homolog, FAST kinase domain-containing protein 2 - Pongo pygmaeus (Orangut...
0.0 [17..709] [1..693]
FAKD2_MOUSE - FAST kinase domain-containing protein 2, mitochondrial OS=Mus musculus GN=Fastkd2 PE=2 SV=2
0.0 [17..706] [1..689]
FAKD2_RAT - FAST kinase domain-containing protein 2, mitochondrial OS=Rattus norvegicus GN=Fastkd2 PE=2 SV=1
0.0 [17..706] [1..679]
gi|40789004 - gi|40789004|dbj|BAA76815.2| KIAA0971 protein [Homo sapiens]
0.0 [1..634] [18..651]
gi|114613232, gi... - gi|114613234|ref|XP_001150522.1| PREDICTED: cell cycle progression 2 protein isoform 8 [Pan troglody...
0.0 [110..702] [29..630]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTTLKPFGS VSVESKMNNK AGSFFWNLRQ FSTLVSTSRT MRLCCLGLCK PKIVHSNWNI  60
   61 LNNFHNRMQS TDIIRYLFQD AFIFKSDVGF QTKGISTLTA LRIERLLYAK RLFFDSKQSL 120
  121 VPVDKSDDEL KKVNLNHEVS NEDVLTKETK P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.425 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.701 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.435 a.118.1 ARM repeat
View Download 0.632 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.480 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore

Predicted Domain #2
Region A:
Residues: [152-266]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRISSRKLSE ECNSLSDVLD AFSKAPTFPS SNYFTAMWTI AKRLSDDQKR FEKRLMFSHP  60
   61 AFNQLCEHMM REAKIMQYKY LLFSLHAIVK LGIPQNTILV QTLLRVTQER INECD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.884 0.575 protein kinase activity a.24.14 FAT domain of focal adhesion kinase
View Download 0.919 0.001 apoptosis a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.947 0.000 apoptosis f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.938 0.000 apoptosis f.18.1 F1F0 ATP synthase subunit A
View Download 0.861 N/A N/A a.24.14 FAT domain of focal adhesion kinase

Predicted Domain #3
Region A:
Residues: [267-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EICLSVLSTV LEAMEPCKNV HVLRTGFRIL VDQQVWKIED VFTLQVVMKC IGKDAPIALK  60
   61 RKLEMKALRE LDRFSVLNSQ HMFEVLAAMN HRSLILLDEC SKVVLDNIHG CPLRIMINIL 120
  121 QSCKDLQYHN LDLFKGLADY VAATFDI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [414-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKFRKVLFIL ILFENLGFRP VGLMDLFMKR IVEDPESLNM KNILSILHTY SSLNHVYKCQ  60
   61 NKEQFVEVMA SALTGYLHTI SSENLLDAVY SFCLMNYFPL APFNQLLQKD IISELLTSDD 120
  121 MKNAYKLHTL 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 30.040959
Match: PF06743.6
Description: No description for PF06743.6 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [544-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTCLKLDDTV YLRDIALSLP QLPRELPSSH TNAKVAEVLS SLLGGEGHFS KDVHLPHNYH  60
   61 IDFEIRMDTN 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 29.69897
Match: PF08368.3
Description: No description for PF08368.3 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [614-710]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNQVLPLSDV DTTSATDIQR VAVLCVSRSA YCLGSSHPRG FLAMKMRHLN AMGFHVILVN  60
   61 NWEMDKLEME DAVTFLKTKI YSVEALPVAA VNVQSTQ

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 19.337242
Match: PF08373.1
Description: No description for PF08373.1 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.406 0.281 apoptosis a.4.5 "Winged helix" DNA-binding domain
View Download 0.438 0.003 apoptosis b.11.1 gamma-Crystallin-like
View Download 0.579 0.001 apoptosis d.74.2 C-terminal domain of arginine repressor
View Download 0.393 0.000 apoptosis a.11.1 Acyl-CoA binding protein
View Download 0.399 N/A N/A d.53.1 Ribosomal protein S3 C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle