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View Structure Prediction Details

Protein: C21orf45
Organism: Homo sapiens
Length: 233 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C21orf45.

Description E-value Query
Range
Subject
Range
MS18A_PANTR - Protein Mis18-alpha OS=Pan troglodytes GN=MIS18A PE=3 SV=1
2.0E-85 [1..233] [1..232]
gi|62657615, gi|... - gi|62657615|ref|XP_221670.3| PREDICTED: similar to 2610039C10Rik protein [Rattus norvegicus], gi|109...
3.0E-81 [1..229] [18..236]
gi|12851734 - gi|12851734|dbj|BAB29147.1| unnamed protein product [Mus musculus]
1.0E-77 [26..229] [3..200]
MS18A_BOVIN - Protein Mis18-alpha OS=Bos taurus GN=MIS18A PE=2 SV=1
4.0E-75 [1..233] [1..235]
gi|74001388 - gi|74001388|ref|XP_852107.1| PREDICTED: similar to Protein C21orf45 [Canis familiaris]
4.0E-71 [1..233] [1..238]
gi|2815610 - gi|2815610|gb|AAC39561.1| Opa-interacting protein OIP5 [Homo sapiens]
2.0E-60 [52..222] [49..222]

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Predicted Domain #1
Region A:
Residues: [1-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGVRSLRCS RGCAGGCECG DKGKCSDSSL LGKRLSEDSS RHQLLQKWAS MWSSMSEDAS  60
   61 VADMERAQLE EEAAAAEERP LVFLCSGCRR PLGDSLSWVA SQEDTNCILL RCVSCNVSVD 120
  121 KEQKLSKREK ENGCVLETLC CAGCSLNLGY VYRCTPKNLD YKRDLFCLSV EAIESYVLGS 180
  181 SEKQIVSEDK ELFNLESRVE IEKSLTQMED VLKALQMKLW EAESKLSFAT CKS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 1l1dA
Description: C-terminal MsrB domain of peptide methionine sulfoxide reductase PilB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.23990229861779 bayes_pls_golite062009
transcription regulator activity 1.56736668601469 bayes_pls_golite062009
nucleic acid binding 1.50544093113513 bayes_pls_golite062009
DNA binding 1.36261752067677 bayes_pls_golite062009
transcription factor activity 0.740498532141188 bayes_pls_golite062009
catalytic activity 0.551815283886794 bayes_pls_golite062009
protein binding 0.343266974610375 bayes_pls_golite062009
cation binding 0.241588214026724 bayes_pls_golite062009
metal ion binding 0.241588214026724 bayes_pls_golite062009
ion binding 0.235349833568887 bayes_pls_golite062009
protein-methionine-R-oxide reductase activity 0.110889211949557 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle