| Protein: | UNC45A |
| Organism: | Homo sapiens |
| Length: | 944 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UNC45A.
| Description | E-value | Query Range |
Subject Range |
|
|
1.0E-95 | [20..944] | [20..944] |
|
|
4.0E-95 | [20..943] | [20..943] |
|
|
8.0E-95 | [1..944] | [1..944] |
|
|
1.0E-94 | [20..944] | [5..929] |
|
|
8.0E-94 | [1..944] | [1..944] |
|
|
8.0E-93 | [20..944] | [5..929] |
|
Region A: Residues: [1-139] |
1 11 21 31 41 51
| | | | | |
1 MTVSGPGTPE PRPATPGASS VEQLRKEGNE LFKCGDYGGA LAAYTQALGL DATPQDQAVL 60
61 HRNRAACHLK LEDYDKAETE ASKAIEKDGG DVKALYRRSQ ALEKLGRLDQ AVLDLQRCVS 120
121 LEPKNKVFQE ALRNIGGQI
|
| Detection Method: |  |
| Confidence: | 19.69897 |
| Match: | 2dbaA |
| Description: | No description for 2dbaA was found. |
|
Region A: Residues: [140-448] |
1 11 21 31 41 51
| | | | | |
1 QEKVRYMSST DAKVEQMFQI LLDPEEKGTE KKQKASQNLV VLAREDAGAE KIFRSNGVQL 60
61 LQRLLDMGET DLMLAALRTL VGICSEHQSR TVATLSILGT RRVVSILGVE SQAVSLAACH 120
121 LLQVMFDALK EGVKKGFRGK EGAIIVDPAR ELKVLISNLL DLLTEVGVSG QGRDNALTLL 180
181 IKAVPRKSLK DPNNSLTLWV IDQGLKKILE VGGSLQDPPG ELAVTANSRM SASILLSKLF 240
241 DDLKCDAERE NFHRLCENYI KSWFEGQGLA GKLRAIQTVS CLLQGPCDAG NRALELSGVM 300
301 ESVIALCAS
|
| Detection Method: | |
| Confidence: | 2.38 |
| Match: | 1wa5B |
| Description: | Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.33303322187387 | bayes_pls_golite062009 |
| protein binding | 1.5114863464349 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.875976248365647 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.73539719922204 | bayes_pls_golite062009 |
| actin binding | 0.552558582632569 | bayes_pls_golite062009 |
| nucleic acid binding | 0.242964024046384 | bayes_pls_golite062009 |
|
Region A: Residues: [449-944] |
1 11 21 31 41 51
| | | | | |
1 EQEEEQLVAV EALIHAAGKA KRASFITANG VSLLKDLYKC SEKDSIRIRA LVGLCKLGSA 60
61 GGTDFSMKQF AEGSTLKLAK QCRKWLCNDQ IDAGTRRWAV EGLAYLTFDA DVKEEFVEDA 120
121 AALKALFQLS RLEERSVLFA VASALVNCTN SYDYEEPDPK MVELAKYAKQ HVPEQHPKDK 180
181 PSFVRARVKK LLAAGVVSAM VCMVKTESPV LTSSCRELLS RVFLALVEEV EDRGTVVAQG 240
241 GGRALIPLAL EGTDVGQTKA AQALAKLTIT SNPEMTFPGE RIYEVVRPLV SLLHLNCSGL 300
301 QNFEALMALT NLAGISERLR QKILKEKAVP MIEGYMFEEH EMIRRAATEC MCNLAMSKEV 360
361 QDLFEAQGND RLKLLVLYSG EDDELLQRAA AGGLAMLTSM RPTLCSRIPQ VTTHWLEILQ 420
421 ALLLSSNQEL QHRGAVVVLN MVEASREIAS TLMESEMMEI LSVLAKGDHS PVTRAAAACL 480
481 DKAVEYGLIQ PNQDGE
|
| Detection Method: | |
| Confidence: | 49.0 |
| Match: | 2bctA |
| Description: | THE ARMADILLO REPEAT REGION FROM MURINE BETA-CATENIN |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.4389817190572 | bayes_pls_golite062009 |
| protein binding | 1.63705839411934 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.01396453014861 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.773975545005505 | bayes_pls_golite062009 |
| actin binding | 0.572473732371314 | bayes_pls_golite062009 |
| nucleic acid binding | 0.294257360897755 | bayes_pls_golite062009 |
| RNA binding | 0.0287526191298597 | bayes_pls_golite062009 |
