YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: DMRT3
Organism: Homo sapiens
Length: 472 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DMRT3.

Description E-value Query
Range
Subject
Range
gi|109111690 - gi|109111690|ref|XP_001089961.1| PREDICTED: similar to doublesex and mab-3 related transcription fac...
1.0E-56 [1..472] [1..472]
gi|109459993 - gi|109459993|ref|XP_219926.4| PREDICTED: similar to doublesex and mab-3 related transcription factor...
4.0E-55 [1..472] [196..671]
gi|114623617 - gi|114623617|ref|XP_528515.2| PREDICTED: doublesex and mab-3 related transcription factor 3 [Pan tro...
5.0E-54 [1..472] [1..472]
gi|25992717, gi|... - gi|28893523|ref|NP_796334.1| doublesex and mab-3 related transcription factor 3 [Mus musculus], gi|2...
3.0E-52 [1..472] [1..476]
gi|73946873 - gi|73946873|ref|XP_851515.1| PREDICTED: similar to doublesex and mab-3 related transcription factor ...
3.0E-46 [1..472] [1..475]
gi|54657094 - gi|54657094|gb|EAL35927.1| DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain [Cryptosporidiu...
gi|67597591 - gi|67597591|ref|XP_666157.1| DNA-directed RNA polymerase II largest chain [Cryptosporidium hominis T...
4.0E-39 [117..420] [1536..1840]
gi|3511287, gi|7... - pir||T31670 DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain - Mastigamoeba invertens (frag...
3.0E-37 [124..393] [1429..1686]
gi|12642614 - gi|12642614|gb|AAK00311.1|AF315821_1 DNA-dependent RNA polymerase II largest subunit RPB1 [Monosiga ...
2.0E-35 [65..390] [1416..1742]

Back

Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGYGSPYLY MGGPVSQPPR APLQRTPKCA RCRNHGVLSW LKGHKRYCRF KDCTCEKCIL  60
   61 IIERQRVMAA QVALRRQQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.78
Match: 1lpvA
Description: DM domain of Doublesex (dsx)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.89235255944902 bayes_pls_golite062009
DNA binding 0.785095407133447 bayes_pls_golite062009
transcription regulator activity 0.695640165807409 bayes_pls_golite062009
nucleic acid binding 0.657150206978452 bayes_pls_golite062009
transcription factor activity 0.602797151961352 bayes_pls_golite062009
protein binding 0.534934440905544 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [79-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANESLESLIP DSLRALPGPP PPGDAVAAPQ PPPASQPSQP QPPRPAAELA AAAALRWTAE  60
   61 PQPGALQAQL AKPDLTEERL GDGKSADNTE VFSDKDTDQR SSPDVA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [185-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSKGCFTPES PEIVSVEEGG YAVQKNGGNP ESRPDSPKCH AEQNHLLIEG PSGTVSLPFS  60
   61 LKANRPPLEV LKKIFPNQKP TVLELILKGC GGDLVSAVEV LLSSRSSVTG AERTSAEPES 120
  121 LALPSNGHIF E

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [316-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTLSSYPISS SKWSVGSAFR VPDTLRFSAD SSNVVPSPLA GPLQPPFPQP PRYPLMLRNT  60
   61 LARSQSSPFL PNDVTLWNTM TLQQQYQLRS QYVSPFPSNS TSVFRSSPVL PARATEDPRI 120
  121 SIPDDGCPFV SKQSIYTEDD YDERSDSSDS RTLNTSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle