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View Structure Prediction Details

Protein: EFTUD2
Organism: Homo sapiens
Length: 972 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EFTUD2.

Description E-value Query
Range
Subject
Range
CG4849-PA - This gene is referred to in FlyBase by the symbol Dmel\CG4849 (CG4849, FBgn0039566). It is a protein...
gi|220956726, gi... - gi|220956726|gb|ACL90906.1| CG4849-PA [synthetic construct], gi|220947200|gb|ACL86143.1| CG4849-PA [...
0.0 [1..972] [1..975]
gi|109122950 - gi|109122950|ref|XP_001118006.1| PREDICTED: eukaryotic translation elongation factor 2 [Macaca mulat...
0.0 [111..957] [577..1434]
gi|157928946, gi... - gi|157928946|gb|ABW03758.1| elongation factor Tu GTP binding domain containing 2 [synthetic construc...
gi|12803113, gi|... - gi|41152056|ref|NP_004238.2| elongation factor Tu GTP binding domain containing 2 [Homo sapiens], gi...
0.0 [1..972] [1..972]
gi|108872311, gi... - gi|157129185|ref|XP_001655314.1| 116 kda U5 small nuclear ribonucleoprotein component [Aedes aegypti...
0.0 [1..972] [1..974]
gi|73965505 - gi|73965505|ref|XP_548058.2| PREDICTED: similar to 116 kDa U5 small nuclear ribonucleoprotein compon...
gi|149723695 - gi|149723695|ref|XP_001489017.1| PREDICTED: similar to 116 kDa U5 small nuclear ribonucleoprotein co...
0.0 [1..972] [1..972]
gi|62657153, gi|... - gi|62657153|ref|XP_213492.3| PREDICTED: similar to 116 kDa U5 small nuclear ribonucleoprotein compon...
0.0 [1..972] [1..972]
U5S1_CHICK - 116 kDa U5 small nuclear ribonucleoprotein component OS=Gallus gallus GN=EFTUD2 PE=2 SV=1
0.0 [1..972] [1..972]
gi|55731935 - gi|55731935|emb|CAH92676.1| hypothetical protein [Pongo abelii]
U5S1_PONAB - 116 kDa U5 small nuclear ribonucleoprotein component OS=Pongo abelii GN=EFTUD2 PE=2 SV=1
0.0 [1..972] [1..972]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTDLYDEFG NYIGPELDSD EDDDELGRET KDLDEMDDDD DDDDVGDHDD DHPGMEVVLH  60
   61 EDKKYYPTAE EVYGPEVETI VQEEDTQPLT EPIIKPVKTK KFTLMEQTLP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.154902
Match: 2hjgA
Description: No description for 2hjgA was found.

Predicted Domain #2
Region A:
Residues: [111-972]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTVYEMDFLA DLMDNSELIR NVTLCGHLHH GKTCFVDCLI EQTHPEIRKR YDQDLCYTDI  60
   61 LFTEQERGVG IKSTPVTVVL PDTKGKSYLF NIMDTPGHVN FSDEVTAGLR ISDGVVLFID 120
  121 AAEGVMLNTE RLIKHAVQER LAVTVCINKI DRLILELKLP PTDAYYKLRH IVDEVNGLIS 180
  181 MYSTDENLIL SPLLGNVCFS SSQYSICFTL GSFAKIYADT FGDINYQEFA KRLWGDIYFN 240
  241 PKTRKFTKKA PTSSSQRSFV EFILEPLYKI LAQVVGDVDT SLPRTLDELG IHLTKEELKL 300
  301 NIRPLLRLVC KKFFGEFTGF VDMCVQHIPS PKVGAKPKIE HTYTGGVDSD LGEAMSDCDP 360
  361 DGPLMCHTTK MYSTDDGVQF HAFGRVLSGT IHAGQPVKVL GENYTLEDEE DSQICTVGRL 420
  421 WISVARYHIE VNRVPAGNWV LIEGVDQPIV KTATITEPRG NEEAQIFRPL KFNTTSVIKI 480
  481 AVEPVNPSEL PKMLDGLRKV NKSYPSLTTK VEESGEHVIL GTGELYLDCV MHDLRKMYSE 540
  541 IDIKVADPVV TFCETVVETS SLKCFAETPN KKNKITMIAE PLEKGLAEDI ENEVVQITWN 600
  601 RKKLGEFFQT KYDWDLLAAR SIWAFGPDAT GPNILVDDTL PSEVDKALLG SVKDSIVQGF 660
  661 QWGTREGPLC DELIRNVKFK ILDAVVAQEP LHRGGGQIIP TARRVVYSAF LMATPRLMEP 720
  721 YYFVEVQAPA DCVSAVYTVL ARRRGHVTQD APIPGSPLYT IKAFIPAIDS FGFETDLRTH 780
  781 TQGQAFSLSV FHHWQIVPGD PLDKSIVIRP LEPQPAPHLA REFMIKTRRR KGLSEDVSIS 840
  841 KFFDDPMLLE LAKQDVVLNY PM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1n0uA
Description: Elongation factor 2 (eEF-2), domain II; Elongation factor 2 (eEF-2), N-terminal (G) domain; Elongation factor 2 (eEF-2), domain IV; Elongation factor 2 (eEF-2)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle