YRC Public Data Repository - Protein Structure Prediction

Protein:	TFF1
Organism:	Homo sapiens
Length:	84 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFF1.

Description	E-value	Query Range	Subject Range
gi\|61365084, gi\|... - gi\|61365084\|gb\|AAX42651.1\| trefoil factor 1 [synthetic construct], gi\|60824999\|gb\|AAX36702.1\| trefoi...	96.0	[0..1]	[84..1]
gi\|182204 - gi\|182204\|gb\|AAA52402.1\| estrogen receptor [Homo sapiens]	93.0	[0..2]	[84..1]
TFF1_RAT - Trefoil factor 1 OS=Rattus norvegicus GN=Tff1 PE=3 SV=1	92.0	[0..4]	[84..1]
gi\|50727979 - gi\|50727979\|ref\|XP_415935.1\| PREDICTED: similar to Maltase-glucoamylase, intestinal [Gallus gallus]	91.0	[0..2]	[76..4]
TFF1_CANLF - Trefoil factor 1 OS=Canis lupus familiaris GN=TFF1 PE=3 SV=1	88.0	[0..4]	[84..1]
gi\|76678173 - gi\|76678173\|ref\|XP_596690.2\| PREDICTED: similar to Maltase-glucoamylase, intestinal, partial [Bos ta...	86.0	[0..15]	[81..48]
gi\|2695845 - gi\|2695845\|emb\|CAA71786.1\| zona pellucida glycoprotein 1 [Callithrix jacchus]	86.0	[0..3]	[84..114]

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Predicted Domain #1

Region A:
Residues: [1-84]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATMENKVIC ALVLVSMLAL GTLAEAQTET CTVAPRERQN CGFPGVTPSQ CANKGCCFDD  60
   61 TVRGVPWCFY PNTIDVPPEE ECEF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.522879
Match:	1hi7A
Description:	PNR-2/PS2, TFF1
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits