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View Structure Prediction Details

Protein: gi|21752839, gi|...
Organism: Homo sapiens
Length: 251 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|21752839, gi|....

Description E-value Query
Range
Subject
Range
gi|114669596 - gi|114669596|ref|XP_001162046.1| PREDICTED: similar to RNA-binding protein Musashi2-S [Pan troglodyt...
6.0E-46 [1..240] [1..240]
gi|73966528 - gi|73966528|ref|XP_532379.2| PREDICTED: similar to musashi 2 isoform a isoform 1 [Canis familiaris]
2.0E-45 [1..240] [1..240]
gi|26341844 - gi|26341844|dbj|BAC34584.1| unnamed protein product [Mus musculus]
1.0E-44 [2..240] [2..240]
gi|123983004, gi... - gi|123997687|gb|ABM86445.1| musashi homolog 2 (Drosophila) [synthetic construct], gi|123983004|gb|AB...
CCDS11596.1_1 - null
MSI2 - musashi homolog 2 (Drosophila)
1.0E-43 [1..240] [1..244]
gi|542646, gi|14... - pir||S40774 ribonucleoprotein - African clawed frog, gi|214936|gb|AAA50004.1| ribonucleoprotein, gi...
1.0E-42 [1..241] [1..245]
gi|109491620 - gi|109491620|ref|XP_001081205.1| PREDICTED: similar to Musashi homolog 2 [Rattus norvegicus]
3.0E-42 [25..240] [191..406]

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Predicted Domain #1
Region A:
Residues: [1-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADLTSVLTS VMFSPSSKMF IGGLSWQTSP DSLRDYFSKF GEIRECMVMR DPTTKRSRGF  60
   61 GFVTFADPAS VDKVLGQPHH ELDSKTIDPK VAFPRRAQPK MVTRTKKIFV GGLSANTVVE 120
  121 DVKQYFEQFG KVEDAMLMFD KTTNRHRGFG FVTFENEDVV EKVCEIHFHE INNKMVECKK 180
  181 AQPKEVMFPP GTRGRARGLP YTMDAFMLGM GMLGYPNFVA TYGRGYPGFA PSYGYQFPDY 240
  241 LPVSQDIIFI N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.69897
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle