YRC Public Data Repository - Protein Structure Prediction

Protein:	HNRNPA0
Organism:	Homo sapiens
Length:	305 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HNRNPA0.

Description	E-value	Query Range	Subject Range
gi\|89266927 - gi\|89266927\|emb\|CAJ82281.1\| ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen ...	5.0E-42	[3..305]	[63..366]
gi\|73971067 - gi\|73971067\|ref\|XP_865045.1\| PREDICTED: similar to ELAV-like 2 isoform 3 isoform 2 [Canis familiaris... gi\|157928304, gi... - gi\|157928304\|gb\|ABW03448.1\| ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen ... gi\|109111348, gi... - gi\|109111352\|ref\|XP_001106502.1\| PREDICTED: similar to ELAV-like 2 isoform 3 isoform 5 [Macaca mulat... ENSPTRT00000045482 - null gi\|119578986, gi... - gi\|55957841\|emb\|CAI13376.1\| ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen ...	5.0E-41	[3..305]	[35..338]
gi\|87650, gi\|36102 - pir\|\|S02061 heterogeneous ribonuclear particle protein A1.beta - human, gi\|36102\|emb\|CAA29922.1\| unn...	2.0E-40	[2..293]	[9..301]
gi\|123857819, gi... - gi\|49114392\|gb\|AAH46598.2\| ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B... IPI:IPI00387625.... - Tax_Id=10116 38 kDa protein, Tax_Id=10116 Gene_Symbol=Elavl2 38 kDa protein	2.0E-40	[3..305]	[35..339]

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Predicted Domain #1

Region A:
Residues: [1-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENSQLCKLF IGGLNVQTSE SGLRGHFEAF GTLTDCVVVV NPQTKRSRCF GFVTYSNVEE  60
   61 ADAAMAASPH AVDGNTVELK RAVSREDSAR PGAHAKVKKL FVGGLKGDVA EGDLIEHFSQ 120
  121 FGTVEKAEII ADKQSGKKRG FGFVYFQNHD AADKAAVVKF HPIQGHRVEV KKAVPKEDIY 180
  181 SGGGGGGSR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.69897
Match:	1pgzA
Description:	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.950788308762215	bayes_pls_golite062009
nucleic acid binding	0.29562225149076	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [190-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSRGGRGGRG RGGGRDQNGL SKGGGGGYNS YGGYGGGGGG GYNAYGGGGG GSSYGGSDYG  60
   61 NGFGGFGSYS QHQSSYGPMK SGGGGGGGGS SWGGRSNSGP YRGGYGGGGG YGGSSF

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.1
Match:	1jchA
Description:	Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: