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View Structure Prediction Details

Protein: RAD21
Organism: Homo sapiens
Length: 631 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD21.

Description E-value Query
Range
Subject
Range
gi|40789064 - gi|40789064|dbj|BAA07554.2| KIAA0078 [Homo sapiens]
0.0 [1..631] [5..635]
gi|109087303, gi... - gi|109087311|ref|XP_001095142.1| PREDICTED: RAD21 homolog isoform 7 [Macaca mulatta], gi|109087309|r...
0.0 [1..631] [1..631]
gi|73974373 - gi|73974373|ref|XP_539142.2| PREDICTED: similar to Double-strand-break repair protein rad21 homolog ...
0.0 [1..631] [1..631]
gi|71043766, gi|... - gi|71043766|ref|NP_001020872.1| RAD21 homolog [Rattus norvegicus], gi|68533861|gb|AAH99200.1| RAD21 ...
0.0 [1..631] [1..635]
gi|74223149, gi|... - gi|74223149|dbj|BAE40713.1| unnamed protein product [Mus musculus], gi|74219960|dbj|BAE40560.1| unna...
0.0 [1..631] [1..635]
RAD21_BOVIN - Double-strand-break repair protein rad21 homolog OS=Bos taurus GN=RAD21 PE=2 SV=1
0.0 [1..631] [1..630]

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Predicted Domain #1
Region A:
Residues: [1-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYAHFVLSK RGPLAKIWLA AHWDKKLTKA HVFECNLESS VESIISPKVK MALRTSGHLL  60
   61 LGVVRIYHRK AKYLLADCNE AFIKIKMAFR PGVVDLPEEN REAAYNAITL PEEFHDFDQP 120
  121 LPDLDDIDVA QQFSLNQSRV EEIT

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 67.920819
Match: PF04825.4
Description: No description for PF04825.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [145-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREEVGNISI LQENDFGDFG MDDREIMREG SAFEDDDMLV STTTSNLLLE SEQSTSNLNE  60
   61 KINHLEYEDQ YKDDNFGEGN DGGILDDKLI SNNDGGIFDD PPALSEAGVM LPEQPAHDDM 120
  121 DEDDNVSMGG PDSPDSVDPV EPMPTMTDQT TLVPNEEEAF A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [306-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEPIDITVKE TKAKRKRKLI VDSVKELDSK TIRAQLSDYS DIVTTLDLAP PTKKLMMWKE  60
   61 TGGVEKLFSL PAQPLWNNRL LKLFTRCLTP LVPEDLRKRR KGGEAD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [412-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLDEFLKEFE NPEVPREDQQ QQHQQRDVID EPIIEEPSRL QESVMEASRT NIDESAMPPP  60
   61 PPQGVKRKAG QIDPEPVMPP QQVEQMEIPP VELPPEEPPN ICQLIPELEL LPEKEKEKEK 120
  121 EKEDDEEEED EDASGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [548-631]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQDQEERRWN KRTQQMLHGL QRALAKTGAE SISLLELCRN TNRKQAAAKF YSFLVLKKQQ  60
   61 AIELTQEEPY SDIIATPGPR FHII

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1w1wE
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.18423275686836 bayes_pls_golite062009
DNA binding 2.00689495715419 bayes_pls_golite062009
nucleic acid binding 1.95069166062856 bayes_pls_golite062009
binding 1.5962792529649 bayes_pls_golite062009
transcription factor activity 1.3352343070618 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle