YRC Public Data Repository - Protein Structure Prediction

Protein:	CDC42EP3
Organism:	Homo sapiens
Length:	254 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC42EP3.

Description	E-value	Query Range	Subject Range
gi\|3834633 - gi\|3834633\|gb\|AAC71773.1\| MSE55-related protein [Homo sapiens]	321.0	[0..1]	[254..1]
gi\|60653989, gi\|... - gi\|60653989\|gb\|AAX29687.1\| CDC42 effector protein 3 [synthetic construct], gi\|30585393\|gb\|AAP36969.1...	321.0	[0..1]	[254..1]
gi\|162287304, gi... - gi\|34862050\|ref\|XP_233815.2\| PREDICTED: similar to CDC42 effector protein (Rho GTPase binding) 3 [Ra...	311.0	[0..1]	[254..1]
gi\|61822521, gi\|... - gi\|86826370\|gb\|AAI12774.1\| CDC42 effector protein (Rho GTPase binding) 3 [Bos taurus], gi\|76677986\|r...	309.0	[0..1]	[254..1]
BORG2_MOUSE - Cdc42 effector protein 3 OS=Mus musculus GN=Cdc42ep3 PE=1 SV=1	307.0	[0..1]	[254..1]
gi\|57098245 - gi\|57098245\|ref\|XP_532935.1\| PREDICTED: similar to Cdc42 effector protein 3 [Canis familiaris]	299.0	[0..1]	[254..1]
gi\|113931486, gi... - gi\|89267414\|emb\|CAJ83192.1\| CDC42 effector protein (Rho GTPase binding) 3 [Xenopus tropicalis], gi\|1...	270.0	[0..1]	[254..1]
gi\|50740824 - gi\|50740824\|ref\|XP_426134.1\| PREDICTED: similar to MSE55-related protein [Gallus gallus]	265.0	[0..1]	[254..1]
gi\|148225632, gi... - gi\|54673689\|gb\|AAH84973.1\| LOC495498 protein [Xenopus laevis], gi\|148225632\|ref\|NP_001088607.1\| hypo...	251.0	[0..1]	[254..1]

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Predicted Domain #1

Region A:
Residues: [1-102]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAKTPIYLK AANNKKGKKF KLRDILSPDM ISPPLGDFRH TIHIGKEGQH DVFGDISFLQ  60
   61 GNYELLPGNQ EKAHLGQFPG HNEFFRANST SDSVFTETPS PV

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	8.619789
Match:	PF00786.19
Description:	No description for PF00786.19 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [103-197]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKNAISLPTI GGSQALMLPL LSPVTFNSKQ ESFGPAKLPR LSCEPVMEEK AQEKSSLLEN  60
   61 GTVHQGDTSW GSSGSASQSS QGRDSHSSSL SEQYP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [198-254]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DWPAEDMFDH PTPCELIKGK TKSEESLSDL TGSLLSLQLD LGPSLLDEVL NVMDKNK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits