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View Structure Prediction Details

Protein: CDC42EP3
Organism: Homo sapiens
Length: 254 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC42EP3.

Description E-value Query
Range
Subject
Range
gi|3834633 - gi|3834633|gb|AAC71773.1| MSE55-related protein [Homo sapiens]
321.0 [0..1] [254..1]
gi|60653989, gi|... - gi|60653989|gb|AAX29687.1| CDC42 effector protein 3 [synthetic construct], gi|30585393|gb|AAP36969.1...
321.0 [0..1] [254..1]
gi|162287304, gi... - gi|34862050|ref|XP_233815.2| PREDICTED: similar to CDC42 effector protein (Rho GTPase binding) 3 [Ra...
311.0 [0..1] [254..1]
gi|61822521, gi|... - gi|86826370|gb|AAI12774.1| CDC42 effector protein (Rho GTPase binding) 3 [Bos taurus], gi|76677986|r...
309.0 [0..1] [254..1]
BORG2_MOUSE - Cdc42 effector protein 3 OS=Mus musculus GN=Cdc42ep3 PE=1 SV=1
307.0 [0..1] [254..1]
gi|57098245 - gi|57098245|ref|XP_532935.1| PREDICTED: similar to Cdc42 effector protein 3 [Canis familiaris]
299.0 [0..1] [254..1]
gi|113931486, gi... - gi|89267414|emb|CAJ83192.1| CDC42 effector protein (Rho GTPase binding) 3 [Xenopus tropicalis], gi|1...
270.0 [0..1] [254..1]
gi|50740824 - gi|50740824|ref|XP_426134.1| PREDICTED: similar to MSE55-related protein [Gallus gallus]
265.0 [0..1] [254..1]
gi|148225632, gi... - gi|54673689|gb|AAH84973.1| LOC495498 protein [Xenopus laevis], gi|148225632|ref|NP_001088607.1| hypo...
251.0 [0..1] [254..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAKTPIYLK AANNKKGKKF KLRDILSPDM ISPPLGDFRH TIHIGKEGQH DVFGDISFLQ  60
   61 GNYELLPGNQ EKAHLGQFPG HNEFFRANST SDSVFTETPS PV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 8.619789
Match: PF00786.19
Description: No description for PF00786.19 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [103-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKNAISLPTI GGSQALMLPL LSPVTFNSKQ ESFGPAKLPR LSCEPVMEEK AQEKSSLLEN  60
   61 GTVHQGDTSW GSSGSASQSS QGRDSHSSSL SEQYP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.254 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.205 g.53.1 TAZ domain
View Download 0.205 g.53.1 TAZ domain

Predicted Domain #3
Region A:
Residues: [198-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DWPAEDMFDH PTPCELIKGK TKSEESLSDL TGSLLSLQLD LGPSLLDEVL NVMDKNK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.787 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.768 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.724 N/A N/A a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.712 N/A N/A a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.661 N/A N/A a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.661 N/A N/A a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.652 N/A N/A a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.650 N/A N/A a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.648 N/A N/A a.189.1 Description not found.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle