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View Structure Prediction Details

Protein: CCL3L1, CCL3L3
Organism: Homo sapiens
Length: 93 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCL3L1, CCL3L3.

Description E-value Query
Range
Subject
Range
gi|164665382, gi... - gi|57527998|ref|NP_001009579.1| chemokine (C-C motif) ligand 3-like 1 [Sus scrofa], gi|49354682|gb|A...
8.0E-27 [1..93] [1..93]
CCL4_MACMU - C-C motif chemokine 4 OS=Macaca mulatta GN=CCL4 PE=2 SV=1
2.0E-26 [1..92] [1..92]
gi|47779271, gi|... - gi|47779271|ref|NP_001001437.1| chemokine (C-C motif) ligand 3-like 3 precursor [Homo sapiens], gi|3...
gi|60656295 - gi|60656295|gb|AAX32711.1| chemokine (C-C motif) ligand 3-like 1 [synthetic construct]
3.0E-26 [1..93] [1..93]
gi|30584489, gi|... - gi|60653245|gb|AAX29317.1| chemokine (C-C motif) ligand 3-like 1 [synthetic construct], gi|60653243|...
3.0E-26 [1..93] [1..93]
CCL4_BOVIN - C-C motif chemokine 4 OS=Bos taurus GN=CCL4 PE=3 SV=1
9.0E-26 [1..92] [1..92]
gi|114671857 - gi|114671857|ref|XP_001172226.1| PREDICTED: similar to Small inducible cytokine A3-like 1 precursor ...
1.0E-25 [2..93] [42..133]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVSTAALAV LLCTMALCNQ VLSAPLAADT PTACCFSYTS RQIPQNFIAD YFETSSQCSK  60
   61 PSVIFLTKRG RQVCADPSEE WVQKYVSDLE LSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1humA
Description: Macrophage inflammatory protein, MIP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytokine activity 8.07273475133641 bayes_pls_golite062009
chemokine receptor binding 7.19574940007631 bayes_pls_golite062009
chemokine activity 7.19574940007631 bayes_pls_golite062009
G-protein-coupled receptor binding 7.12866319987718 bayes_pls_golite062009
receptor binding 5.70505228637425 bayes_pls_golite062009
protein binding 3.96178206863622 bayes_pls_golite062009
interleukin-8 receptor binding 3.86135397575984 bayes_pls_golite062009
binding 3.44333267537536 bayes_pls_golite062009
chemoattractant activity 3.05299139114464 bayes_pls_golite062009
heparin binding 2.48790323783525 bayes_pls_golite062009
glycosaminoglycan binding 1.80091312295242 bayes_pls_golite062009
CCR2 chemokine receptor binding 1.78317158345185 bayes_pls_golite062009
polysaccharide binding 1.28416986663426 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.2394639113112 bayes_pls_golite062009
kinase activity 1.20242374860894 bayes_pls_golite062009
protein kinase activity 1.20167556785693 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.05370662506053 bayes_pls_golite062009
pattern binding 1.02739535268516 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.0107537553708 bayes_pls_golite062009
CCR chemokine receptor binding 0.697359799598971 bayes_pls_golite062009
carbohydrate binding 0.14673741350408 bayes_pls_golite062009
catalytic activity 0.11400259673574 bayes_pls_golite062009
transporter activity 0.0541029584618528 bayes_pls_golite062009

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