YRC Public Data Repository - Protein Structure Prediction

Protein:	MAB21L2
Organism:	Homo sapiens
Length:	359 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAB21L2.

Description	E-value	Query Range	Subject Range
gi\|224049331 - gi\|224049331\|ref\|XP_002186952.1\| PREDICTED: similar to mab-21-like 2 [Taeniopygia guttata] tr\|M3X8D1\|M3X8D1... - Mab-21 like 2 OS=Felis catus GN=MAB21L2 PE=4 SV=1 gi\|57097275 - gi\|57097275\|ref\|XP_539761.1\| PREDICTED: similar to mab-21-like 2 isoform 1 [Canis familiaris] MB212_MOUSE - Protein mab-21-like 2 OS=Mus musculus GN=Mab21l2 PE=2 SV=1 gi\|61821253 - gi\|61821253\|ref\|XP_585738.1\| PREDICTED: similar to mab-21-like 2 isoform 1 [Bos taurus] gi\|149698169 - gi\|149698169\|ref\|XP_001501615.1\| PREDICTED: similar to mab-21-like 2 [Equus caballus] gi\|149640453 - gi\|149640453\|ref\|XP_001513820.1\| PREDICTED: hypothetical protein [Ornithorhynchus anatinus] gi\|126331311 - gi\|126331311\|ref\|XP_001366703.1\| PREDICTED: hypothetical protein [Monodelphis domestica] gi\|27693879, gi\|... - ref\|XP_227492.1\| similar to mab-21-like protein 2; mab-21-like 2 [Rattus norvegicus], gi\|157820693\|...	0.0	[1..359]	[1..359]
gi\|9964007 - gi\|9964007\|gb\|AAG09800.1\|AF262032_1 MAB21L2 protein [Homo sapiens]	0.0	[1..359]	[1..359]
gi\|47227852 - gi\|47227852\|emb\|CAG09015.1\| unnamed protein product [Tetraodon nigroviridis]	0.0	[1..359]	[1..359]
MB211_DANRE - Protein mab-21-like 1 OS=Danio rerio GN=mab21l1 PE=2 SV=1	0.0	[1..359]	[1..359]
M212B_XENLA - Protein mab-21-like 2-B OS=Xenopus laevis GN=mab21l2-b PE=2 SV=1	0.0	[1..359]	[1..359]

Back

Predicted Domain #1

Region A:
Residues: [1-359]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAAQAKLVY QLNKYYTERC QARKAAIAKT IREVCKVVSD VLKEVEVQEP RFISSLSEID  60
   61 ARYEGLEVIS PTEFEVVLYL NQMGVFNFVD DGSLPGCAVL KLSDGRKRSM SLWVEFITAS 120
  121 GYLSARKIRS RFQTLVAQAV DKCSYRDVVK MIADTSEVKL RIRERYVVQI TPAFKCTGIW 180
  181 PRSAAQWPMP HIPWPGPNRV AEVKAEGFNL LSKECYSLTG KQSSAESDAW VLQFGEAENR 240
  241 LLMGGCRNKC LSVLKTLRDR HLELPGQPLN NYHMKTLLLY ECEKHPRETD WDESCLGDRL 300
  301 NGILLQLISC LQCRRCPHYF LPNLDLFQGK PHSALESAAK QTWRLAREIL TNPKSLDKL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.54
Match:	1px5A
Description:	Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.53356592031109	bayes_pls_golite062009
protein binding	1.20472171285911	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.893478989935841	bayes_pls_golite062009
nucleic acid binding	0.766163328557144	bayes_pls_golite062009
nucleotidyltransferase activity	0.378944807711308	bayes_pls_golite062009
DNA binding	0.294396132196589	bayes_pls_golite062009
transcription factor binding	0.0365937361646029	bayes_pls_golite062009
transferase activity	0.02609645275331	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: