| Protein: | WEE1 |
| Organism: | Homo sapiens |
| Length: | 646 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WEE1.
| Description | E-value | Query Range |
Subject Range |
|
|
9.0E-88 | [1..646] | [1..646] |
|
|
2.0E-87 | [1..646] | [1..646] |
|
|
1.0E-84 | [1..646] | [1..646] |
|
|
4.0E-82 | [1..646] | [241..887] |
|
|
3.0E-79 | [1..646] | [1..646] |
|
|
5.0E-79 | [1..646] | [1..646] |
|
|
8.0E-78 | [298..642] | [19..340] |
|
Region A: Residues: [1-278] |
1 11 21 31 41 51
| | | | | |
1 MSFLSRQQPP PPRRAGAACT LRQKLIFSPC SDCEEEEEEE EEEGSGHSTG EDSAFQEPDS 60
61 PLPPARSPTE PGPERRRSPG PAPGSPGELE EDLLLPGACP GADEAGGGAE GDSWEEEGFG 120
121 SSSPVKSPAA PYFLGSSFSP VRCGGPGDAS PRGCGARRAG EGRRSPRPDH PGTPPHKTFR 180
181 KLRLFDTPHT PKSLLSKARG IDSSSVKLRG SSLFMDTEKS GKREFDVRQT PQVNINPFTP 240
241 DSLLLHSSGQ CRRRKRTYWN DSCGEDMEAS DYELEDET
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [279-578] |
1 11 21 31 41 51
| | | | | |
1 RPAKRITITE SNMKSRYTTE FHELEKIGSG EFGSVFKCVK RLDGCIYAIK RSKKPLAGSV 60
61 DEQNALREVY AHAVLGQHSH VVRYFSAWAE DDHMLIQNEY CNGGSLADAI SENYRIMSYF 120
121 KEAELKDLLL QVGRGLRYIH SMSLVHMDIK PSNIFISRTS IPNAASEEGD EDDWASNKVM 180
181 FKIGDLGHVT RISSPQVEEG DSRFLANEVL QENYTHLPKA DIFALALTVV CAAGAEPLPR 240
241 NGDQWHEIRQ GRLPRIPQVL SQEFTELLKV MIHPDPERRP SAMALVKHSV LLSASRKSAE 300
301
|
| Detection Method: | |
| Confidence: | 50.30103 |
| Match: | 1x8bA |
| Description: | Structure of human Wee1A kinase: kinase domain complexed with inhibitor PD0407824 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [579-646] |
1 11 21 31 41 51
| | | | | |
1 QLRIELNAEK FKNSLLQKEL KKAQMAKAAA EERALFTDRM ATRSTTQSNR TSRLIGKKMN 60
61 RSVSLTIY
|
| Detection Method: | |
| Confidence: | 59.0 |
| Match: | 1omwA |
| Description: | G-protein coupled receptor kinase 2, N-terminal domain; G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1); G-protein coupled receptor kinase 2 |
Matching Structure (courtesy of the PDB): |
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