






| Protein: | EIF3L |
| Organism: | Homo sapiens |
| Length: | 564 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EIF3L.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..564] | [44..607] |
|
|
0.0 | [1..564] | [1..564] |
|
|
0.0 | [1..564] | [1..564] |
|
|
0.0 | [1..564] | [1..564] |
|
Region A: Residues: [1-124] |
1 11 21 31 41 51
| | | | | |
1 MSYPADDYES EAAYDPYAYP SDYDMHTGDP KQDLAYERQY EQQTYQVIPE VIKNFIQYFH 60
61 KTVSDLIDQK VYELQASRVS SDVIDQKVYE IQDIYENSWT KLTERFFKNT PWPEAEAIAP 120
121 QVGN
|
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.791 | 0.793 | nucleoplasm | a.22.1 | Histone-fold |
| View | Download | 0.658 | 0.132 | nucleoplasm | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.625 | 0.003 | protein binding | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.620 | N/A | N/A | a.22.1 | Histone-fold |
| View | Download | 0.581 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
|
Region A: Residues: [125-217] |
1 11 21 31 41 51
| | | | | |
1 DAVFLILYKE LYYRHIYAKV SGGPSLEQRF ESYYNYCNLF NYILNADGPA PLELPNQWLW 60
61 DIIDEFIYQF QSFSQYRCKT AKKSEEEIDF LRS
|
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.704 | 0.034 | nucleolus | a.7.1 | Spectrin repeat |
| View | Download | 0.817 | 0.034 | nucleolus | a.7.8 | GAT domain |
| View | Download | 0.920 | 0.034 | nucleolus | a.24.3 | Cytochromes |
| View | Download | 0.733 | 0.034 | nucleolus | a.24.3 | Cytochromes |
| View | Download | 0.708 | 0.034 | nucleolus | a.24.3 | Cytochromes |
|
Region A: Residues: [218-373] |
1 11 21 31 41 51
| | | | | |
1 NPKIWNVHSV LNVLHSLVDK SNINRQLEVY TSGGDPESVA GEYGRHSLYK MLGYFSLVGL 60
61 LRLHSLLGDY YQAIKVLENI ELNKKSMYSR VPECQVTTYY YVGFAYLMMR RYQDAIRVFA 120
121 NILLYIQRTK SMFQRTTYKY EMINKQNEQM HALLAI
|
| Detection Method: | |
| Confidence: | 1.22 |
| Match: | 2hr2A |
| Description: | No description for 2hr2A was found. |
| Term | Confidence | Notes |
| binding | 2.50062202757362 | bayes_pls_golite062009 |
| protein binding | 1.72061787550863 | bayes_pls_golite062009 |
| nucleic acid binding | 1.03214696367403 | bayes_pls_golite062009 |
| transcription regulator activity | 1.0247488240855 | bayes_pls_golite062009 |
| DNA binding | 0.812129701902081 | bayes_pls_golite062009 |
| transcription factor activity | 0.142011117504773 | bayes_pls_golite062009 |
|
Region A: Residues: [374-564] |
1 11 21 31 41 51
| | | | | |
1 ALTMYPMRID ESIHLQLREK YGDKMLRMQK GDPQVYEELF SYSCPKFLSP VVPNYDNVHP 60
61 NYHKEPFLQQ LKVFSDEVQQ QAQLSTIRSF LKLYTTMPVA KLAGFLDLTE QEFRIQLLVF 120
121 KHKMKNLVWT SGISALDGEF QSASEVDFYI DKDMIHIADT KVARRYGDFF IRQIHKFEEL 180
181 NRTLKKMGQR P
|
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.576 | 0.091 | nucleolus | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.653 | 0.018 | nucleolus | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.484 | 0.011 | nucleolus | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.649 | 0.010 | nucleolus | d.110.2 | GAF domain-like |
| View | Download | 0.537 | 0.004 | nucleolus | a.50.1 | Anaphylotoxins (complement system) |