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View Structure Prediction Details

Protein: NIP7
Organism: Homo sapiens
Length: 180 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NIP7.

Description E-value Query
Range		 Subject
Range
gi|76640106 - gi|76640106|ref|XP_587055.2| PREDICTED: similar to 60S ribosome subunit biogenesis protein NIP7 homo...
 2.0E-97 [1..180] [1..180]
NIP7_PIG - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Sus scrofa GN=NIP7 PE=2 SV=1
 2.0E-97 [1..180] [1..180]
NIP7_RAT - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Rattus norvegicus GN=Nip7 PE=2 SV=1
 8.0E-97 [1..180] [1..180]
NIP7_MOUSE - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Mus musculus GN=Nip7 PE=1 SV=1
 1.0E-96 [1..180] [1..180]
gi|57087185 - gi|57087185|ref|XP_536804.1| PREDICTED: similar to 60S ribosome subunit biogenesis protein NIP7 homo...
 2.0E-96 [1..180] [1..180]
NIP7_XENLA - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Xenopus laevis GN=nip7 PE=2 SV=1
 4.0E-96 [1..180] [1..180]
NIP7_TETNG - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Tetraodon nigroviridis GN=nip7 PE=3 SV=1
 4.0E-94 [1..180] [1..180]
gi|62737983 - gi|62737983|pdb|1SQW|A Chain A, Crystal Structure Of Kd93, A Novel Protein Expressed In The Human Pr...
 6.0E-94 [1..174] [1..174]

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Predicted Domain #1
Region A:
Residues: [1-180] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPLTEEETR VMFEKIAKYI GENLQLLVDR PDGTYCFRLH NDRVYYVSEK IMKLAANISG  60
   61 DKLVSLGTCF GKFTKTHKFR LHVTALDYLA PYAKYKVWIK PGAEQSFLYG NHVLKSGLGR 120
  121 ITENTSQYQG VVVYSMADIP LGFGVAAKST QDCRKVDPMA IVVFHQADIG EYVRHEETLT 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.69897
Match: 1t5yA
Description: Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.67504868533195 bayes_pls_golite062009
binding 1.85616760502339 bayes_pls_golite062009
nucleic acid binding 1.26170105245043 bayes_pls_golite062009
transcription regulator activity 1.25899985044692 bayes_pls_golite062009
DNA binding 1.00086161863786 bayes_pls_golite062009
transcription factor activity 0.459074630080185 bayes_pls_golite062009
protein binding 0.377070376016177 bayes_pls_golite062009
ligase activity 0.365702917579223 bayes_pls_golite062009
catalytic activity 0.147263815852997 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle