| Protein: | TSC1 |
| Organism: | Homo sapiens |
| Length: | 1164 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TSC1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1164] | [1..1164] |
|
|
0.0 | [1..1164] | [1..1167] |
|
|
0.0 | [1..1164] | [1..1163] |
|
|
0.0 | [1..1164] | [1..1163] |
|
|
0.0 | [1..1164] | [1..1161] |
|
|
0.0 | [1..478] | [1..477] |
|
|
0.0 | [1..1164] | [1..1163] |
|
Region A: Residues: [1-194] |
1 11 21 31 41 51
| | | | | |
1 MAQQANVGEL LAMLDSPMLG VRDDVTAVFK ENLNSDRGPM LVNTLVDYYL ETSSQPALHI 60
61 LTTLQEPHDK HLLDRINEYV GKAATRLSIL SLLGHVIRLQ PSWKHKLSQA PLLPSLLKCL 120
121 KMDTDVVVLT TGVLVLITML PMIPQSGKQH LLDFFDIFGR LSSWCLKKPG HVAEVYLVHL 180
181 HASVYALFHR LYGM
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [195-305] |
1 11 21 31 41 51
| | | | | |
1 YPCNFVSFLR SHYSMKENLE TFEEVVKPMM EHVRIHPELV TGSKDHELDP RRWKRLETHD 60
61 VVIECAKISL DPTEASYEDG YSVSHQISAR FPHRSADVTT SPYADTQNSY G
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [306-396] |
1 11 21 31 41 51
| | | | | |
1 CATSTPYSTS RLMLLNMPGQ LPQTLSSPST RLITEPPQAT LWSPSMVCGM TTPPTSPGNV 60
61 PPDLSHPYSK VFGTTAGGKG TPLGTPATSP P
|
| Detection Method: | |
| Confidence: | 6.522879 |
| Match: | 2tmaA |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [397-738] |
1 11 21 31 41 51
| | | | | |
1 PAPLCHSDDY VHISLPQATV TPPRKEERMD SARPCLHRQH HLLNDRGSEE PPGSKGSVTL 60
61 SDLPGFLGDL ASEEDSIEKD KEEAAISREL SEITTAEAEP VVPRGGFDSP FYRDSLPGSQ 120
121 RKTHSAASSS QGASVNPEPL HSSLDKLGPD TPKQAFTPID LPCGSADESP AGDRECQTSL 180
181 ETSIFTPSPC KIPPPTRVGF GSGQPPPYDH LFEVALPKTA HHFVIRKTEE LLKKAKGNTE 240
241 EDGVPSTSPM EVLDRLIQQG ADAHSKELNK LPLPSKSVDW THFGGSPPSD EIRTLRDQLL 300
301 LLHNQLLYER FKRQQHALRN RRLLRKVIKA AALEEHNAAM KD
|
| Detection Method: | |
| Confidence: | 24.0 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [739-907] |
1 11 21 31 41 51
| | | | | |
1 QLKLQEKDIQ MWKVSLQKEQ ARYNQLQEQR DTMVTKLHSQ IRQLQHDREE FYNQSQELQT 60
61 KLEDCRNMIA ELRIELKKAN NKVCHTELLL SQVSQKLSNS ESVQQQMEFL NRQLLVLGEV 120
121 NELYLEQLQN KHSDTTKEVE MMKAAYRKEL EKNRSHVLQQ TQRLDTSQK
|
| Detection Method: | |
| Confidence: | 4.69897 |
| Match: | 2i1jA |
| Description: | No description for 2i1jA was found. |
|
Region A: Residues: [908-1049] |
1 11 21 31 41 51
| | | | | |
1 RILELESHLA KKDHLLLEQK KYLEDVKLQA RGQLQAAESR YEAQKRITQV FELEILDLYG 60
61 RLEKDGLLKK LEEEKAEAAE AAEERLDCCN DGCSDSMVGH NEEASGHNGE TKTPRPSSAR 120
121 GSSGSRGGGG SSSSSSELST PE
|
| Detection Method: | |
| Confidence: | 1.33 |
| Match: | 1x79B |
| Description: | Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1050-1164] |
1 11 21 31 41 51
| | | | | |
1 KPPHQRAGPF SSRWETTMGE ASASIPTTVG SLPSSKSFLG MKARELFRNK SESQCDEDGM 60
61 TSSLSESLKT ELGKDLGVEA KIPLNLDGPH PSPPTPDSVG QLHIMDYNET HHEHS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
