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View Structure Prediction Details

Protein: H1FX
Organism: Homo sapiens
Length: 213 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for H1FX.

Description E-value Query
Range
Subject
Range
gi|27436873, gi|... - gi|27436873|ref|NP_775105.1| SNF2 histone linker PHD RING helicase isoform b [Homo sapiens], gi|2736...
3.0E-33 [39..201] [433..616]
gi|114609682 - gi|114609682|ref|XP_001172960.1| PREDICTED: SNF2 histone linker PHD RING helicase isoform 3 [Pan tro...
8.0E-33 [39..201] [322..505]
gi|26343465 - gi|26343465|dbj|BAC35389.1| unnamed protein product [Mus musculus]
8.0E-32 [39..197] [428..603]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVELEEALP VTTAEGMAKK VTKAGGSAAL SPSKKRKNSK KKNQPGKYSQ LVVETIRRLG  60
   61 ERNGSSLAKI YTEAKKVPWF DQQNGRTYLK YSIKALVQND TLLQVKGTGA NGSFKLNRKK 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.522879
Match: 1hstA
Description: Histone H5, globular domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.835523092977445 bayes_pls_golite062009
transcription regulator activity 0.4843036104266 bayes_pls_golite062009
nucleic acid binding 0.37117756729668 bayes_pls_golite062009
DNA binding 0.3118855114645 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [121-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEGGGERRGA PAAATAPAPT AHKAKKAAPG AAGSRRADKK PARGQKPEQR SHKKGAGAKK  60
   61 DKGGKAKKTA AAGGKKVKKA AKPSVPKVPK GRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle