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View Structure Prediction Details

Protein: AANAT
Organism: Homo sapiens
Length: 207 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AANAT.

Description E-value Query
Range
Subject
Range
SNAT_MESAU - Serotonin N-acetyltransferase OS=Mesocricetus auratus GN=AANAT PE=2 SV=1
9.0E-46 [1..207] [1..207]
gi|21666079 - gi|21666079|gb|AAM73553.1|AF317891_1 arylalkylamine-N-acetyl-transferase [Arvicanthis niloticus]
9.0E-45 [1..207] [1..207]
gi|76645766 - gi|76645766|ref|XP_876019.1| PREDICTED: similar to Serotonin N-acetyltransferase (Aralkylamine N-ace...
2.0E-44 [1..205] [265..469]
SNAT_MOUSE - Serotonin N-acetyltransferase OS=Mus musculus GN=Aanat PE=2 SV=1
1.0E-43 [3..207] [1..205]
SNAT_RAT - Serotonin N-acetyltransferase OS=Rattus norvegicus GN=Aanat PE=1 SV=1
2.0E-43 [3..207] [1..205]
gi|112443187 - gi|112443187|gb|ABI18977.1| arylalkylamine-N-acetyltransferase [Bos grunniens]
4.0E-42 [1..205] [1..205]
SNAT_PANTR - Serotonin N-acetyltransferase OS=Pan troglodytes GN=AANAT PE=2 SV=1
6.0E-41 [1..207] [1..207]
SNAT_SHEEP - Serotonin N-acetyltransferase OS=Ovis aries GN=AANAT PE=1 SV=1
7.0E-41 [1..205] [1..205]
gi|56122230 - gi|56122230|gb|AAV74266.1| arylalkylamine N-acetyltransferase [Saimiri boliviensis]
2.0E-40 [1..207] [1..207]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTQSTHPLK PEAPRLPPGI PESPSCQRRH TLPASEFRCL TPEDAVSAFE IEREAFISVL  60
   61 GVCPLYLDEI RHFLTLCPEL SLGWFEEGCL VAFIIGSLWD KERLMQESLT LHRSGGHIAH 120
  121 LHVLAVHRAF RQQGRGPILL WRYLHHLGSQ PAVRRAALMC EDALVPFYER FSFHAVGPCA 180
  181 ITVGSLTFME LHCSLRGHPF LRRNSGC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.30103
Match: 1kuvA
Description: Serotonin N-acetyltranferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.97933499002461 bayes_pls_golite062009
transferase activity 1.72447231774431 bayes_pls_golite062009
N-acyltransferase activity 1.55647009430432 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 1.47571666298157 bayes_pls_golite062009
acyltransferase activity 1.47230586550141 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.42711272311757 bayes_pls_golite062009
acetyltransferase activity 0.823367673029436 bayes_pls_golite062009
N-acetyltransferase activity 0.498634717186713 bayes_pls_golite062009
binding 0.387003868530186 bayes_pls_golite062009
diamine N-acetyltransferase activity 0.0228522669982662 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle