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View Structure Prediction Details

Protein: RAD9A
Organism: Homo sapiens
Length: 391 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD9A.

Description E-value Query
Range
Subject
Range
gi|49168502 - gi|49168502|emb|CAG38746.1| RAD9A [Homo sapiens]
0.0 [1..391] [1..391]
gi|109105212 - gi|109105212|ref|XP_001106622.1| PREDICTED: similar to RAD9 homolog isoform 2 [Macaca mulatta]
0.0 [1..391] [1..390]
RAD9A_MOUSE - Cell cycle checkpoint control protein RAD9A OS=Mus musculus GN=Rad9a PE=1 SV=1
0.0 [1..391] [1..389]
RAD9A_MACFA - Cell cycle checkpoint control protein RAD9A OS=Macaca fascicularis GN=RAD9A PE=2 SV=1
0.0 [13..391] [2..379]
gi|73983605 - gi|73983605|ref|XP_540817.2| PREDICTED: similar to RAD9 homolog [Canis familiaris]
0.0 [1..391] [114..503]
gi|59857657, gi|... - gi|59857657|gb|AAX08663.1| RAD9 homolog [Bos taurus], gi|146186911|gb|AAI40699.1| RAD9A protein [Bos...
0.0 [1..391] [1..422]

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Predicted Domain #1
Region A:
Residues: [1-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKCLVTGGNV KVLGKAVHSL SRIGDELYLE PLEDGLSLRT VNSSRSAYAC FLFAPLFFQQ  60
   61 YQAATPGQDL LRCKILMKSF LSVFRSLAML EKTVEKCCIS LNGRSSRLVV QLHCKFGVRK 120
  121 THNLSFQDCE SLQAVFDPAS CPHMLRAPAR VLGEAVLPFS PALAEVTLGI GRGRRVILRS 180
  181 YHEEEADSTA KAMVTEMCLG EEDFQQLQAQ EGVAITFCLK EFRGLLSFAE SANLNLSIHF 240
  241 DAPGRPAIFT IKDSLLDGHF VLATLSDTDS HSQDLGSPER H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.69897
Match: 1axcA
Description: Prolifirating cell nuclear antigen (PCNA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA polymerase activity 4.03805427520849 bayes_pls_golite062009
DNA-directed DNA polymerase activity 4.03676997767928 bayes_pls_golite062009
nucleotidyltransferase activity 2.73498799665327 bayes_pls_golite062009
DNA binding 2.06316167255592 bayes_pls_golite062009
nucleic acid binding 2.02054974752473 bayes_pls_golite062009
binding 1.88302251910664 bayes_pls_golite062009
protein binding 1.50334902588177 bayes_pls_golite062009
DNA polymerase processivity factor activity 1.3525144557927 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.82032718298306 bayes_pls_golite062009
catalytic activity 0.48077242755678 bayes_pls_golite062009
structure-specific DNA binding 0.252286203059537 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [282-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPVPQLQAHS TPHPDDFAND DIDSYMIAME TTIGNEGSRV LPSISLSPGP QPPKSPGPHS  60
   61 EEEDEAEPST VPGTPPPKKF RSLFFGSILA PVRSPQGPSP VLAEDSEGEG 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 1pk8A
Description: Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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