






| Protein: | FXN |
| Organism: | Homo sapiens |
| Length: | 210 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FXN.
| Description | E-value | Query Range |
Subject Range |
|
|
2.0E-92 | [1..210] | [1..210] |
|
|
5.0E-90 | [1..210] | [1..210] |
|
|
1.0E-89 | [1..210] | [1..210] |
|
|
3.0E-88 | [1..210] | [1..210] |
|
|
3.0E-84 | [1..208] | [1..206] |
|
|
9.0E-84 | [1..208] | [1..205] |
|
Region A: Residues: [1-89] |
1 11 21 31 41 51
| | | | | |
1 MWTLGRRAVA GLLASPSPAQ AQTLTRVPRP AELAPLCGRR GLRTDIDATC TPRRASSNQR 60
61 GLNQIWNVKK QSVYLMNLRK SGTLGHPGS
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [90-210] |
1 11 21 31 41 51
| | | | | |
1 LDETTYERLA EETLDSLAEF FEDLADKPYT FEDYDVSFGS GVLTVKLGGD LGTYVINKQT 60
61 PNKQIWLSSP SSGPKRYDWT GKNWVYSHDG VSLHELLAAE LTKALKTKLD LSSLAYSGKD 120
121 A
|
| Detection Method: | |
| Confidence: | 48.69897 |
| Match: | 1ekgA |
| Description: | C-terminal domain of frataxin |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| iron chaperone activity | 4.16905358201916 | bayes_pls_golite062009 |
| ferric iron binding | 3.23865994858009 | bayes_pls_golite062009 |
| iron ion binding | 2.78584553912929 | bayes_pls_golite062009 |
| 2 iron, 2 sulfur cluster binding | 2.25545886640675 | bayes_pls_golite062009 |
| transition metal ion binding | 1.85229574432416 | bayes_pls_golite062009 |
| binding | 1.75179885686234 | bayes_pls_golite062009 |
| metallochaperone activity | 1.67572555512957 | bayes_pls_golite062009 |
| ferrous iron binding | 1.61332056179381 | bayes_pls_golite062009 |
| protein binding | 1.50639308293007 | bayes_pls_golite062009 |
| cation binding | 1.42164579673909 | bayes_pls_golite062009 |
| metal ion binding | 1.42164579673909 | bayes_pls_golite062009 |
| ion binding | 1.4150396069236 | bayes_pls_golite062009 |
| oxidoreductase activity | 1.07282105096776 | bayes_pls_golite062009 |
| metal cluster binding | 0.602901470550009 | bayes_pls_golite062009 |
| iron-sulfur cluster binding | 0.602901470550009 | bayes_pls_golite062009 |
| oxidoreductase activity, oxidizing metal ions, oxygen as acceptor | 0.310374472796773 | bayes_pls_golite062009 |
| ferroxidase activity | 0.310374472796773 | bayes_pls_golite062009 |
| catalytic activity | 0.276917867171685 | bayes_pls_golite062009 |