YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: HIST1H1E
Organism: Homo sapiens
Length: 219 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIST1H1E.

Description E-value Query
Range
Subject
Range
gi|70878483 - gi|70878483|gb|EAN91735.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71649745 - gi|71649745|ref|XP_813586.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
3.0E-31 [2..218] [780..999]
gi|10334767 - gi|10334767|gb|AAG16729.1|AF252857_1 factor H-binding inhibitor of complement surface protein PspC [...
4.0E-25 [4..219] [265..476]
gi|116126363, gi... - gi|118786522|ref|XP_315475.3| ENSANGP00000021721 [Anopheles gambiae str. PEST], gi|116126363|gb|EAA1...
1.0E-23 [3..218] [1018..1245]

Back

Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETAPAAPA APAPAEKTPV KKKARKSAGA AKRKASGPPV SELITKAVAA SKERSGVSLA  60
   61 ALKKALAAAG YDVEKNNSRI KLGLKSLVSK GTLVQTKGTG ASGSFKLNKK AASGEAKPKA 120
  121 K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 1ghcA
Description: HOMO-AND HETERONUCLEAR TWO-DIMENSIONAL NMR STUDIES OF THE GLOBULAR DOMAIN OF HISTONE H1: FULL ASSIGNMENT, TERTIARY STRUCTURE, AND COMPARISON WITH THE GLOBULAR DOMAIN OF HISTONE H5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.835523092977445 bayes_pls_golite062009
transcription regulator activity 0.4843036104266 bayes_pls_golite062009
nucleic acid binding 0.37117756729668 bayes_pls_golite062009
DNA binding 0.3118855114645 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [122-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAGAAKAKKP AGAAKKPKKA TGAATPKKSA KKTPKKAKKP AAAAGAKKAK SPKKAKAAKP  60
   61 KKAPKSPAKA KAVKPKAAKP KTAKPKAAKP KKAAAKKK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.91
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle