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View Structure Prediction Details

Protein: gi|119630903, gi...
Organism: Homo sapiens
Length: 566 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119630903, gi....

Description E-value Query
Range
Subject
Range
gi|243486 - gi|243486|gb|AAB21139.1| p63 [Homo sapiens]
615.0 [0..1] [566..1]
gi|114680699, gi... - gi|114680701|ref|XP_001162666.1| PREDICTED: hypothetical protein isoform 15 [Pan troglodytes], gi|11...
613.0 [0..1] [566..1]
gi|30584239, gi|... - gi|60653191|gb|AAX29290.1| cell division cycle 25B [synthetic construct], gi|30584239|gb|AAP36368.1|...
606.0 [0..1] [566..1]
gi|248473 - gi|248473|gb|AAB22026.1| Cdc25M2 [Mus sp.]
MPIP2_MOUSE - M-phase inducer phosphatase 2 OS=Mus musculus GN=Cdc25b PE=1 SV=1
598.0 [0..1] [566..1]
gi|7435156 - gi|7435156|pir||I66868 cdc25B - rat
MPIP2_RAT - M-phase inducer phosphatase 2 OS=Rattus norvegicus GN=Cdc25b PE=1 SV=1
586.0 [0..1] [566..1]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVPQPEPAP GSALSPAGVC GGAQRPGHLP GLLLGSHGLL GSPVRAAASS PVTTLTQTMH  60
   61 DLAGLGSRSR LTHLSLSRRA SESSLSSESS ESSDAGLCMD SPSPMDPHMA EQTF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQAIQAASRI IRNEQFAIRR FQSMPVRLLG HSPVLRNITN SQAPDGRRKS EAGSGAASSS  60
   61 GEDKENDGFV FKMPWKPTHP SSTHALAEWA SRREAFAQRP SSAPDLMCLS PDRKMEVEEL 120
  121 SPLALGRFSL TPAEGDTEED DGF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [258-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDILESDLKD DDAVPPGMES LISAPLVKTL EKEEEKDLVM YSKCQRLFRS PSMPCSVIRP  60
   61 ILKRLERPQD RDTPVQNKRR RSV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [341-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPPEEQQEAE EPKARVLRSK SLCHDEIENL LDSDHRELIG DYSKAFLLQT VDGKHQDLKY  60
   61 ISPETMVALL TGKFSNIVDK FVIVDCRYPY EYEGGHIKTA VNLPLERDAE SFLLKSPIAP 120
  121 CSLDKRVILI FHCEFSSERG PRMCRFIRER DRAVNDYPSL YYPEMYILKG GYKEFFPQHP 180
  181 NFCEPQDYRP MNHEAFKDEL KTFRLKTRSW AGERSRRELC SRLQDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.30103
Match: 1cwrA
Description: CDC25b
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle