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View Structure Prediction Details

Protein: gi|119630903, gi...
Organism: Homo sapiens
Length: 566 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119630903, gi....

Description E-value Query
Range
Subject
Range
gi|243486 - gi|243486|gb|AAB21139.1| p63 [Homo sapiens]
615.0 [0..1] [566..1]
gi|114680699, gi... - gi|114680701|ref|XP_001162666.1| PREDICTED: hypothetical protein isoform 15 [Pan troglodytes], gi|11...
613.0 [0..1] [566..1]
gi|30584239, gi|... - gi|60653191|gb|AAX29290.1| cell division cycle 25B [synthetic construct], gi|30584239|gb|AAP36368.1|...
606.0 [0..1] [566..1]
gi|248473 - gi|248473|gb|AAB22026.1| Cdc25M2 [Mus sp.]
MPIP2_MOUSE - M-phase inducer phosphatase 2 OS=Mus musculus GN=Cdc25b PE=1 SV=1
598.0 [0..1] [566..1]
gi|7435156 - gi|7435156|pir||I66868 cdc25B - rat
MPIP2_RAT - M-phase inducer phosphatase 2 OS=Rattus norvegicus GN=Cdc25b PE=1 SV=1
586.0 [0..1] [566..1]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVPQPEPAP GSALSPAGVC GGAQRPGHLP GLLLGSHGLL GSPVRAAASS PVTTLTQTMH  60
   61 DLAGLGSRSR LTHLSLSRRA SESSLSSESS ESSDAGLCMD SPSPMDPHMA EQTF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.266 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.266 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.221 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.212 N/A N/A c.23.1 CheY-like

Predicted Domain #2
Region A:
Residues: [115-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQAIQAASRI IRNEQFAIRR FQSMPVRLLG HSPVLRNITN SQAPDGRRKS EAGSGAASSS  60
   61 GEDKENDGFV FKMPWKPTHP SSTHALAEWA SRREAFAQRP SSAPDLMCLS PDRKMEVEEL 120
  121 SPLALGRFSL TPAEGDTEED DGF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [258-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDILESDLKD DDAVPPGMES LISAPLVKTL EKEEEKDLVM YSKCQRLFRS PSMPCSVIRP  60
   61 ILKRLERPQD RDTPVQNKRR RSV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.642 N/A N/A a.64.1 Saposin
View Download 0.576 N/A N/A a.64.1 Saposin
View Download 0.454 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.406 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.325 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.316 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.298 N/A N/A a.8.9 Description not found.
View Download 0.283 N/A N/A a.83.1 Guanido kinase N-terminal domain
View Download 0.269 N/A N/A a.60.1 SAM/Pointed domain

Predicted Domain #4
Region A:
Residues: [341-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPPEEQQEAE EPKARVLRSK SLCHDEIENL LDSDHRELIG DYSKAFLLQT VDGKHQDLKY  60
   61 ISPETMVALL TGKFSNIVDK FVIVDCRYPY EYEGGHIKTA VNLPLERDAE SFLLKSPIAP 120
  121 CSLDKRVILI FHCEFSSERG PRMCRFIRER DRAVNDYPSL YYPEMYILKG GYKEFFPQHP 180
  181 NFCEPQDYRP MNHEAFKDEL KTFRLKTRSW AGERSRRELC SRLQDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.30103
Match: 1cwrA
Description: CDC25b
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle