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View Structure Prediction Details

Protein: UBE2Q2
Organism: Homo sapiens
Length: 375 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBE2Q2.

Description E-value Query
Range
Subject
Range
gi|114658247 - gi|114658247|ref|XP_001145531.1| PREDICTED: ubiquitin-conjugating enzyme E2Q (putative) 2 isoform 4 ...
0.0 [1..375] [1..375]
gi|109484735 - gi|109484735|ref|XP_001072896.1| PREDICTED: similar to ubiquitin-conjugating enzyme E2Q 2 [Rattus no...
0.0 [1..375] [221..597]
UB2Q2_MOUSE - Ubiquitin-conjugating enzyme E2 Q2 OS=Mus musculus GN=Ube2q2 PE=2 SV=2
0.0 [1..375] [1..378]
UB2Q2_RABIT - Ubiquitin-conjugating enzyme E2 Q2 OS=Oryctolagus cuniculus GN=UBE2Q2 PE=2 SV=1
0.0 [1..375] [1..369]
gi|38014428, gi|... - gi|38014428|gb|AAH60407.1| MGC68587 protein [Xenopus laevis], gi|148223748|ref|NP_001083463.1| hypot...
0.0 [1..375] [1..368]
gi|55742509, gi|... - gi|89273817|emb|CAJ83659.1| novel protein [Xenopus tropicalis], gi|55742509|ref|NP_001006696.1| ubiq...
gi|55742509 - ref|NP_001006696.1| ubiquitin-conjugating enzyme E2Q (putative) [Xenopus tropicalis]
0.0 [1..375] [1..368]

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Predicted Domain #1
Region A:
Residues: [1-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVSGLKAEL KFLASIFDKN HERFRIVSWK LDELHCQFLV PQQGSPHSLP PPLTLHCNIT  60
   61 ESYPSSSPIW FVDSEDPNLT SVLERLEDTK NNNLLRQQLK WLICELCSLY NLPKHLDVEM 120
  121 LDQPLPTGQN GTTEEVTSEE EEEEEEMAED IEDLDHYEMK EEEPISGKKS EDEGIEKENL 180
  181 AILEKIRK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 1ylaA
Description: Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 0.469169254031451 bayes_pls_golite062009
binding 0.44075344288274 bayes_pls_golite062009
small conjugating protein ligase activity 0.35936785933411 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.108796735243525 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [189-375]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQRQDHLNGA VSGSVQASDR LMKELRDIYR SQSYKTGIYS VELINDSLYD WHVKLQKVDP  60
   61 DSPLHSDLQI LKEKEGIEYI LLNFSFKDNF PFDPPFVRVV LPVLSGGYVL GGGALCMELL 120
  121 TKQGWSSAYS IESVIMQINA TLVKGKARVQ FGANKNQYNL ARAQQSYNSI VQIHEKNGWY 180
  181 TPPKEDG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.221849
Match: 1zuoA
Description: Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in Embryo Attachment and Implantation
Matching Structure (courtesy of the PDB):

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