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View Structure Prediction Details

Protein: TIGD2
Organism: Homo sapiens
Length: 525 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIGD2.

Description E-value Query
Range
Subject
Range
gi|34860486, gi|... - gi|34860486|ref|XP_235818.2| PREDICTED: similar to jerky homolog-like [Rattus norvegicus], gi|157822...
0.0 [1..521] [1..521]
JERKL_MOUSE - Jerky protein homolog-like OS=Mus musculus GN=Jrkl PE=2 SV=1
0.0 [1..521] [1..520]
JRKL - jerky homolog-like (mouse)
0.0 [1..522] [1..522]
gi|109108409 - gi|109108409|ref|XP_001094262.1| PREDICTED: similar to jerky homolog-like [Macaca mulatta]
0.0 [1..522] [1..522]
gi|57102284 - gi|57102284|ref|XP_533970.1| PREDICTED: similar to jerky homolog-like [Canis familiaris]
0.0 [1..522] [1..522]
gi|76619573 - gi|76619573|ref|XP_610945.2| PREDICTED: similar to tigger transposable element derived 2 [Bos taurus...
0.0 [1..525] [1..525]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGKRKRVVL TIKDKLDIIK KLEEGISFKK LSVVYGIGES TVRDIKKNKE RIINYANSSD  60
   61 PTSGVSKRKS MKSSTYEELD RVMIEWFNQQ KTDGIPVSGT ICAKQAKFFF DALGMEGDFN 120
  121 ASSGWLTRFK QRHGIPKAAG KGTKLKG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.522879
Match: 1hlvA
Description: DNA-binding domain of centromere binding protein B (CENP-B)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [148-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DETAAREFCG SFQEFVEKEN LQPEQIYGAD QTGLFWKCLP SRTLTLETDQ STSGCRSSRE  60
   61 RIIIMCCANA TGLHKLNLCV VGKAKKPRAF KGTDLSNLPV TYYSQKGAWI EQSVFRQWFE 120
  121 KYFVPQVQKH LKSKGLLEKA VLLLDFPPAR PNEEMLSSDD GRIIVKYLPP NVTSLIQPMS 180
  181 QGVLATVKRY YRAGLLQKYM DEGNDPKIFW KNLTVLDAIY EVSRAWNMVK SSTITKAWKK 240
  241 LFPGN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.77
Match: 2f7tA
Description: No description for 2f7tA was found.

Predicted Domain #3
Region A:
Residues: [393-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EENSGMNIDE GAILAANLAT VLQNTEECEH VDIENIDQWF DSRSSDSSCQ VLTDSESAED  60
   61 QTKAAEQKPS SKSRKTELNP EKHISHKAAL EWTENLLDYL EQQDDMLLSD KLVLRRLRTI 120
  121 IRKKQKIQNN KNH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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