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View Structure Prediction Details

Protein: XCL1
Organism: Homo sapiens
Length: 114 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XCL1.

Description E-value Query
Range
Subject
Range
gi|60832995 - gi|60832995|gb|AAX37032.1| chemokine (C motif) ligand 2 [synthetic construct]
1.0E-25 [1..114] [1..114]
gi|74136447, gi|... - gi|74136447|ref|NP_001028119.1| chemokine (C motif) ligand 1 [Macaca mulatta], gi|25987932|gb|AAN760...
1.0E-25 [1..114] [1..114]
XCL2 - chemokine (C motif) ligand 2
2.0E-25 [1..114] [1..114]
gi|114565221 - gi|114565221|ref|XP_524955.2| PREDICTED: similar to CD8+T cell specific protein [Pan troglodytes]
2.0E-25 [1..114] [1..114]
gi|2144879, gi|5... - gi|595909|gb|AAA56752.1| lymphotactin, pir||ETMSL lymphotactin precursor - mouse
6.0E-24 [1..114] [1..114]
gi|55531 - gi|55531|emb|CAA34901.1| JE product [Rattus sp.]
CCL2_RAT - C-C motif chemokine 2 OS=Rattus norvegicus GN=Ccl2 PE=2 SV=1
5.0E-22 [1..109] [1..115]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLILALLG ICSLTAYIVE GVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF  60
   61 ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 1j8iA
Description: Lymphotactin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
chemokine activity 4.88837469516253 bayes_pls_golite062009
chemokine receptor binding 4.88837469516253 bayes_pls_golite062009
cytokine activity 4.54210263594448 bayes_pls_golite062009
G-protein-coupled receptor binding 4.42511063737115 bayes_pls_golite062009
binding 2.743598287572 bayes_pls_golite062009
receptor binding 2.56904769297015 bayes_pls_golite062009
protein binding 2.19284956337197 bayes_pls_golite062009
chemoattractant activity 1.08487334922776 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.623182191143301 bayes_pls_golite062009
signal transducer activity 0.00314411474321696 bayes_pls_golite062009
molecular transducer activity 0.00314411474321696 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle