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View Structure Prediction Details

Protein: gi|1335029, gi|1...
Organism: Homo sapiens
Length: 348 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1335029, gi|1....

Description E-value Query
Range
Subject
Range
gi|109072789 - gi|109072789|ref|XP_001101267.1| PREDICTED: similar to myeloblastosis proto-oncogene product isoform...
2.0E-90 [1..347] [86..423]
gi|114609513 - gi|114609513|ref|XP_518756.2| PREDICTED: v-myb myeloblastosis viral oncogene homolog [Pan troglodyte...
1.0E-89 [9..347] [448..777]
gi|45502015 - gi|45502015|emb|CAE55174.1| v-myb myeloblastosis viral oncogene homologue (avian) [Homo sapiens]
9.0E-88 [8..347] [7..337]
gi|73946020 - gi|73946020|ref|XP_541112.2| PREDICTED: similar to myeloblastosis proto-oncogene product isoform 2 [...
5.0E-86 [8..347] [131..461]

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Predicted Domain #1
Region A:
Residues: [1-34]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSTHSYFCSI YSSDEDDEDF EMCDHDYDGL LPKS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [35-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKRHLGKTRW TREEDEKLKK LVEQNGTDDW KVIANYLPNR TDVQCQHRWQ KVLNPELIKG  60
   61 PWTKEEDQRV IELVQKYGPK RWSVIAKHLK GRIGKQCRER WHNHLNPEVK KTSWTEEEDR 120
  121 IIYQAHKRLG NRWAEIAKLL PGRTDNAIKN HWNSTMRRKV EQEGYLQESS KASQPAVATS 180
  181 FQKNSHLMGF AQAPPTAQLP ATGQPTVNND YSYYHISEAQ NVSSHVPYPV ALHVNIVNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.30103
Match: 1h88C
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.334577365229545 bayes_pls_golite062009
transcription regulator activity 0.0696342306231097 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [274-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQPAAAAIQR HYNDEDPEKE KRIKELELLL MSTENELKGQ QLCGPLLNSD IFSDWAANWD  60
   61 GSLCFATYIV NQQRQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle