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View Structure Prediction Details

Protein: WASF2
Organism: Homo sapiens
Length: 498 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WASF2.

Description E-value Query
Range
Subject
Range
gi|70878103 - gi|70878103|gb|EAN91386.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71648919 - gi|71648919|ref|XP_813237.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
3.0E-45 [3..498] [714..1209]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
2.0E-41 [2..488] [874..1367]
SLAP1_CLOTH - Cell surface glycoprotein 1 OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 ...
2.0E-40 [2..498] [1480..1993]
WASF4 - WAS protein family, member 4
5.0E-40 [2..498] [130..625]
gi|111306009, gi... - gi|118403872|ref|NP_001072263.1| WAS protein family, member 3 [Xenopus (Silurana) tropicalis], gi|11...
2.0E-38 [1..498] [1..502]
gi|162318520, gi... - gi|162319640|gb|AAI57066.1| WAS protein family, member 2 [synthetic construct], gi|162318520|gb|AAI5...
WASF2_MOUSE - Wiskott-Aldrich syndrome protein family member 2 OS=Mus musculus GN=Wasf2 PE=1 SV=1
2.0E-36 [1..498] [1..497]

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Predicted Domain #1
Region A:
Residues: [1-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLVTRNIEP RHLCRQTLPS VRSELECVTN ITLANVIRQL GSLSKYAEDI FGELFTQANT  60
   61 FASRVSSLAE RVDRLQVKVT QLDPKEEEVS LQGINTRKAF RSSTIQDQKL FDRNSLPVPV 120
  121 LETYNTCDTP PPLNNLTPYR DDGKEALKFY TDPSYFFDLW KEKMLQDTKD IMKEKRKHRK 180
  181 EKKDNPNRGN VNPRKIKTRK EEWEKMKMGQ EFVESKEKLG T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [222-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGYPPTLVYQ NGSIGCVENV DASSYPPPPQ SDSASSPSPS FSEDNLPPPP AEFSYPVDNQ  60
   61 RGSGLAGPKR SSVVSPSHPP PAPPLGSPPG PKPGFAPPPA PPPPPPPMIG IPPPPPPVGF 120
  121 GSPGTPPPPS PPSFPPHPDF AAPPPPPPPP AADYPTLPPP PLSQPTGGAP PPPPPPPPPG 180
  181 PPPPPFTG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [410-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADGQPAIPPP LSDTTKPKSS LPAVSDARSD LLSAIRQGFQ LRRVEEQREQ EKRDVVGNDV  60
   61 ATILSRRIAV EYSDSEDDSS EFDEDDWSD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.486 d.58.1 4Fe-4S ferredoxins
View Download 0.573 a.64.1 Saposin
View Download 0.486 a.50.1 Anaphylotoxins (complement system)
View Download 0.448 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.388 a.64.1 Saposin


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