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View Structure Prediction Details

Protein: RANGRF
Organism: Homo sapiens
Length: 186 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RANGRF.

Description E-value Query
Range
Subject
Range
gi|149053011, gi... - gi|27672836|ref|XP_213367.1| PREDICTED: similar to RAN guanine nucleotide release factor [Rattus nor...
2.0E-85 [1..186] [1..185]
gi|109113207 - gi|109113207|ref|XP_001112740.1| PREDICTED: similar to RAN guanine nucleotide release factor isoform...
3.0E-84 [1..186] [1..186]
MOG1_MOUSE - Ran guanine nucleotide release factor OS=Mus musculus GN=Rangrf PE=1 SV=1
8.0E-84 [1..186] [1..185]
gi|7106862 - gi|7106862|gb|AAF36156.1|AF151070_1 HSPC236 [Homo sapiens]
5.0E-83 [1..186] [1..185]
MOG1_BOVIN - Ran guanine nucleotide release factor OS=Bos taurus GN=RANGRF PE=2 SV=1
2.0E-78 [1..186] [1..186]
gi|73955636 - gi|73955636|ref|XP_849976.1| PREDICTED: similar to RAN guanine nucleotide release factor isoform 2 [...
7.0E-76 [1..186] [1..186]

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Predicted Domain #1
Region A:
Residues: [1-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPTRDCPLF GGAFSAILPM GAIDVSDLRP VPDNQEVFCH PVTDQSLIVE LLELQAHVRG  60
   61 EAAARYHFED VGGVQGARAV HVESVQPLSL ENLALRGRCQ EAWVLSGKQQ IAKENQQVAK 120
  121 DVTLHQALLR LPQYQTDLLL TFNQPPPDNR SSLGPENLSP APWSLGDFEQ LVTSLTLHDP 180
  181 NIFGPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.0
Match: 1eq6A
Description: Ran-binding protein mog1p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
Ran GTPase binding 3.83186198399075 bayes_pls_golite062009
small GTPase binding 2.75440466170666 bayes_pls_golite062009
GTPase binding 2.73134262031387 bayes_pls_golite062009
binding 2.4093171025758 bayes_pls_golite062009
Ras GTPase binding 2.22184304825623 bayes_pls_golite062009
protein binding 1.15557714383339 bayes_pls_golite062009
enzyme binding 1.03098126048798 bayes_pls_golite062009
GTPase regulator activity 0.943196151179532 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.933840306327072 bayes_pls_golite062009
enzyme regulator activity 0.527133092574879 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.514094253633343 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle