YRC Public Data Repository - Protein Structure Prediction

Protein:	PCH2
Organism:	Saccharomyces cerevisiae
Length:	536 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PCH2.

Description	E-value	Query Range	Subject Range
gi\|7435750 - pir\|\|B69512 cell division control protein 48, AAA family (cdc48-2) homolog - Archaeoglobus fulgidus gi\|2648442, gi\|1... - gi\|2648442\|gb\|AAB89157.1\| cell division control protein 48, AAA family (cdc48-2) [Archaeoglobus fulg...	0.0	[3..536]	[278..778]
gi\|3257095, gi\|1... - gi\|3257095\|dbj\|BAA29778.1\| 840aa long hypothetical cell division control protein (transitional endop... gi\|7435754 - pir\|\|H71114 probable cell division control protein (transitional endoplasmic reticulum ATPase) - Pyr...	0.0	[3..524]	[293..774]
gi\|7435762, gi\|5... - pir\|\|D75046 transitional endoplasmic reticulum atpase PAB1478 - Pyrococcus abyssi (strain Orsay), gi... gi\|5458778, gi\|1... - gi\|5458778\|emb\|CAB50265.1\| ATPase of the AAA+ family [Pyrococcus abyssi GE5], gi\|14521559\|ref\|NP_127...	0.0	[3..519]	[293..769]
gi\|18977335, gi\|... - gi\|18977335\|ref\|NP_578692.1\| cell division protein CDC48 [Pyrococcus furiosus DSM 3638], gi\|18893012...	0.0	[3..524]	[290..771]
gi\|6513847 - gi\|6513847\|dbj\|BAA87866.1\| Pk-cdcA [Thermococcus kodakaraensis] gi\|57640604, gi\|... - gi\|6513847\|dbj\|BAA87866.1\| Pk-cdcA [Thermococcus kodakaraensis], gi\|57640604\|ref\|YP_183082.1\| cell d...	0.0	[3..519]	[290..765]
CI111_ARATH - Calmodulin-interacting protein 111 OS=Arabidopsis thaliana GN=CIP111 PE=1 SV=1	0.0	[6..536]	[468..969]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[6..536]	[468..969]

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Predicted Domain #1

Region A:
Residues: [1-221]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYIVDLQVR GSSLRVIKCM FREDEQISSL HSGSDSKQNS NKKLGEFLNL LKAVVKRKLE  60
   61 SFPKDRLKTS IITGQELMRE GQGSIEIKDP PTEAQQHLIR SLAKVLLHQF SSINGKVNTV 120
  121 NEGQDNLFLS LFVKKISIEQ QSTSHVSIKL NFHEKINLGQ HIDSILDSEE TNESDTYHMG 180
  181 SVDEFIIYPF CCLEEQDELK NGSILSTEFD KIDLELDEDD G

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [222-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEGETLNNCI NSVGNFDIPL SKQTLNLVNI SYLPGTTFEG QWESLYFGNN IKERLYSYAT  60
   61 ISLKIARFKQ TGDSNQEDIT TLITNNKLLL VHGPPGTGKT TLCKALCQKL SVRREFSDGS 120
  121 DTIDTNYKGI IIELSCARIF SKWFGESSKN ISIVFKDIEE LLKVNEGRGI FICLLIDEVE 180
  181 AIASSRTNLS SRNESTDGIR VVNTLLTQLD RLKKYHNFLA LATSNLLDSL DDAFVDRADG 240
  241 VFYVGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	177.69897
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [468-536]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTAEGILHIL KVCIEEMITS GIILFHARST GVKFFNKYQD ILRKIAIKCS VCFFLLFYFY  60
   61 DSFSFFPSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	177.69897
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits