YRC Public Data Repository - Protein Structure Prediction

Protein:	SPT14
Organism:	Saccharomyces cerevisiae
Length:	461 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPT14.

Description	E-value	Query Range	Subject Range
SPT14 - UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosp...	0.0	[1..461]	[1..461]
gi\|38327651, gi\|... - gi\|38327651\|ref\|NP_035211.1\| phosphatidylinositol glycan, class A [Mus musculus], gi\|26328103\|dbj\|BA...	0.0	[12..461]	[33..484]
PIGA - phosphatidylinositol glycan anchor biosynthesis, class A	0.0	[10..461]	[31..483]
gi\|28919533, gi\|... - gi\|32419927\|ref\|XP_330407.1\| hypothetical protein [Neurospora crassa], gi\|28919533\|gb\|EAA28961.1\| ph... gi\|85089974 - gi\|85089974\|ref\|XP_958197.1\| phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit [Neur...	0.0	[13..457]	[6..511]
GPI3_SCHPO - Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit OS=Schizosaccharomyces pombe (stra... gpi3 - pig-A	3.0E-98	[16..445]	[1..419]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	1.0E-96	[16..429]	[1..414]
gi\|18407913, gi\|... - gi\|30692535\|ref\|NP_850658.1\| SETH2; transferase, transferring glycosyl groups [Arabidopsis thaliana]...	3.0E-96	[8..445]	[3..427]
CE03109 - phosphatidylinositol biosynthetic protein status:Partially_confirmed UniProt:Q18993 protein_id:CAA91...	2.0E-94	[11..454]	[7..432]
gi\|8571458 - gi\|8571458\|gb\|AAF76891.1\| PIG-A [Paramecium tetraurelia]	4.0E-94	[13..440]	[3..418]

Back

Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSHKVESY NNENRMLCDF FYPQLGGVEF HIYHLSQKLI DLGHSVVIIT HAYKDRVGVR  60
   61 HLTNGLKVYH VPFFVIFRET TFPTVFSTFP IIRNILLREQ IQIVHSHGSA STFAHEGILH 120
  121 ANTMGLRTVF TDHSLYGFNN LTSIWVNKLL TFTLTNIDRV ICVSNTCKEN MIVRTELSPD 180
  181 IISVI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.69897
Match:	1f0kA_
Description:	Peptidoglycan biosynthesys glycosyltransferase MurG
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [186-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNAVVSEDFK PRDPTGGTKR KQSRDKIVIV VIGRLFPNKG SDLLTRIIPK VCSSHEDVEF  60
   61 IVAGDGPKFI DFQQMIESHR LQKRVQLLGS VPHEKVRDVL CQGDIYLHAS LTEAFGTILV 120
  121 EAASCNLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.69897
Match:	1f0kA_
Description:	Peptidoglycan biosynthesys glycosyltransferase MurG
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [314-461]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVTTQVGGIP EVLPNEMTVY AEQTSVSDLV QATNKAINII RSKALDTSSF HDSVSKMYDW  60
   61 MDVAKRTVEI YTNISSTSSA DDKDWMKMVA NLYKRDGIWA KHLYLLCGIV EYMLFFLLEW 120
  121 LYPRDEIDLA PKWPKKTVSN ETKEARET

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits