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View Structure Prediction Details

Protein: CYC2
Organism: Saccharomyces cerevisiae
Length: 366 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYC2.

Description E-value Query
Range
Subject
Range
gi|11119241 - gi|11119241|gb|AAG30576.1|AF314093_1 nitrate reductase [Ricinus communis]
6.0E-53 [17..352] [613..911]
gi|24474446 - gi|24474446|gb|AAN15927.1| nitrate reductase [Tilia platyphyllos]
8.0E-53 [13..352] [594..891]
gi|470678 - gi|470678|gb|AAA18377.1| NADH:nitrate reductase
9.0E-52 [18..352] [341..637]
NIA2_PHAVU - Nitrate reductase [NADH] 2 OS=Phaseolus vulgaris GN=NIA2 PE=3 SV=1
2.0E-51 [19..352] [568..887]
gi|47086667, gi|... - gi|94733424|emb|CAK04217.1| novel protein (zgc:77071) [Danio rerio], gi|47086667|ref|NP_997850.1| cy...
3.0E-51 [53..345] [27..289]
gi|220674 - gi|220674|dbj|BAA00530.1| NADH-cytochrome b5 reductase [Rattus sp.]
NB5R3_RAT - NADH-cytochrome b5 reductase 3 OS=Rattus norvegicus GN=Cyb5r3 PE=1 SV=2
4.0E-51 [49..350] [26..297]
gi|14041825 - gi|14041825|dbj|BAB55002.1| nitrate reductase [Prunus persica]
5.0E-51 [9..352] [607..903]

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Predicted Domain #1
Region A:
Residues: [1-366]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLWKNYVLSS SRITRRLHKS PRKSSFSKNF FITGCLLTVG AVSSYLTYRY TSERENKHEL  60
   61 SPSYFVKYKI SHKRDIDSSH FLLEVTPLFK QKVNIWSLMT AENLWSVEIK QPEVMVVRNY 120
  121 TPLPLKFNPA SKEIEILKDG DNADGKLSFY IKKYENGEVA RWLHHLPKGH IIEIRGPFID 180
  181 YEFPHLPNEL KRSRDCLYMD NRNERGNNVR ENSQFIYQPY DIMMFTAGTG IVTALQLLLT 240
  241 ESPFRGTIKL FHTDKNIKQL GPLYPILLRL QASNRVQLKI FETDRQTKQD VLKSIQKSIT 300
  301 KPYPYKGLLP FSNVNNKNIM PVLALVCGPE SYISSISGRK YDLNQGPVGG LLSKEGWNSD 360
  361 NVYKLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.0
Match: 1ndh__
Description: cytochrome b5 reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ferredoxin-NADP+ reductase activity 1.46342400843015 bayes_pls_golite062009
ferredoxin reductase activity 1.46342400843015 bayes_pls_golite062009
oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor 1.46342400843015 bayes_pls_golite062009
catalytic activity 1.45374095556065 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor 1.42015329094031 bayes_pls_golite062009
binding 1.1846867809187 bayes_pls_golite062009
transferase activity 1.15480450573972 bayes_pls_golite062009
cytochrome-b5 reductase activity 1.03329517603164 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 0.90349352746963 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.837374174980467 bayes_pls_golite062009
protein binding 0.452115023569428 bayes_pls_golite062009
adenyl nucleotide binding 0.380728782547069 bayes_pls_golite062009
riboflavin synthase activity 0.380537461428523 bayes_pls_golite062009
coenzyme binding 0.377407140593246 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 0.316225866055591 bayes_pls_golite062009
oxidoreductase activity 0.27336340260908 bayes_pls_golite062009
purine nucleotide binding 0.178246305574472 bayes_pls_golite062009
nucleotide binding 0.172202492581267 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle