YRC Public Data Repository - Protein Structure Prediction

Protein:	SCJ1
Organism:	Saccharomyces cerevisiae
Length:	377 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCJ1.

Description	E-value	Query Range	Subject Range
DNAJ_PSEPK - Chaperone protein DnaJ OS=Pseudomonas putida (strain KT2440) GN=dnaJ PE=3 SV=1 tr\|E4R635\|E4R635... - Chaperone protein DnaJ OS=Pseudomonas putida (strain BIRD-1) GN=dnaJ PE=3 SV=1	1.0E-91	[19..377]	[1..347]
gi\|107103857 - gi\|107103857\|ref\|ZP_01367775.1\| hypothetical protein PaerPA_01004928 [Pseudomonas aeruginosa PACS2] DNAJ_PSEA8 - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain LESB58) GN=dnaJ PE=3 SV=1 DNAJ_PSEAE - Chaperone protein dnaJ OS=Pseudomonas aeruginosa GN=dnaJ PE=3 SV=1 DNAJ_PSEAB - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=dnaJ PE=3 SV=1 DNAJ_PSEAE - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 1222... gi\|194549490, gi... - gi\|84317360\|ref\|ZP_00965808.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|126197717, gi... - gi\|84323584\|ref\|ZP_00971653.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...	2.0E-90	[19..376]	[1..348]
DNAJ_LEGPN - Chaperone protein DnaJ OS=Legionella pneumophila GN=dnaJ PE=3 SV=1 DNAJ_LEGPC - Chaperone protein DnaJ OS=Legionella pneumophila (strain Corby) GN=dnaJ PE=3 SV=1 DNAJ_LEGPA - Chaperone protein DnaJ OS=Legionella pneumophila (strain Paris) GN=dnaJ PE=3 SV=1 DNAJ_LEGPH - Chaperone protein DnaJ OS=Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33...	3.0E-90	[19..377]	[1..348]
DNAJ_AGRFC - Chaperone protein DnaJ OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=dnaJ PE=2 SV=2 gi\|25296037, gi\|... - pir\|\|AD2591 molecular chaperone, DnaJ family dnaJ [imported] - Agrobacterium tumefaciens (strain C58...	5.0E-90	[19..376]	[1..351]
gi\|188495716, gi... - gi\|75515606\|ref\|ZP_00737763.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|168785065, gi... - gi\|189374927\|gb\|EDU93343.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC869], gi\|1687850... sp\|B7UI60\|DNAJ_ECO27 - Chaperone protein dnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_SHISS - Chaperone protein DnaJ OS=Shigella sonnei (strain Ss046) GN=dnaJ PE=3 SV=1 gi\|168762775, gi... - gi\|189366928\|gb\|EDU85344.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC4501], gi\|168762... gi\|192956076, gi... - gi\|75234578\|ref\|ZP_00718919.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECOSM - Chaperone protein DnaJ OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=dnaJ PE=3 SV=1 gi\|193065637, gi... - gi\|75256327\|ref\|ZP_00727999.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|189379547, gi... - gi\|189379547\|gb\|EDU97963.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC508], gi\|1687979... DNAJ_ECO27 - Chaperone protein DnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOSE - Chaperone protein DnaJ OS=Escherichia coli (strain SE11) GN=dnaJ PE=3 SV=1 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6 GN=dnaJ PE=2 SV=3 DNAJ_ESCF3 - Chaperone protein DnaJ OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=dn... gi\|217325343, gi... - gi\|217325343\|ref\|ZP_03441427.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. TW14588], gi\|2... DNAJ_ECOUT - Chaperone protein DnaJ OS=Escherichia coli (strain UTI89 / UPEC) GN=dnaJ PE=3 SV=1 gi\|15829269, gi\|... - gi\|15829269\|ref\|NP_308042.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. Sakai], gi\|133594... gi\|75229476, gi\|... - gi\|75229476\|ref\|ZP_00716026.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|75235742, gi\|... - gi\|75235742\|ref\|ZP_00719906.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECO24 - Chaperone protein DnaJ OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOHS - Chaperone protein DnaJ OS=Escherichia coli O9:H4 (strain HS) GN=dnaJ PE=3 SV=1 gi\|209747186, gi... - pir\|\|G85481 chaperone with DnaK, heat shock protein [imported] - Escherichia coli (strain O157:H7, s... DNAJ_ECO57 - Chaperone protein DnaJ OS=Escherichia coli O157:H7 GN=dnaJ PE=3 SV=3 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=dnaJ PE=3 S... DNAJ_ECO45 - Chaperone protein DnaJ OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|12512693, gi\|... - gi\|15799695\|ref\|NP_285707.1\| chaperone protein DnaJ [Escherichia coli O157:H7 EDL933], gi\|12512693\|g... DNAJ_ECO8A - Chaperone protein DnaJ OS=Escherichia coli O8 (strain IAI1) GN=dnaJ PE=3 SV=1 DNAJ_ECO55 - Chaperone protein DnaJ OS=Escherichia coli (strain 55989 / EAEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO81 - Chaperone protein DnaJ OS=Escherichia coli O81 (strain ED1a) GN=dnaJ PE=3 SV=1 DNAJ_ECOLU - Chaperone protein DnaJ OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO7I - Chaperone protein DnaJ OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|227837919, gi... - gi\|227885090\|ref\|ZP_04002895.1\| chaperone protein DnaJ [Escherichia coli 83972], gi\|227837919\|gb\|EEJ... gi\|229560216 - gi\|229560216\|ref\|YP_667956.2\| chaperone protein DnaJ [Escherichia coli 536] gi\|229775981 - gi\|229775981\|ref\|YP_851221.2\| chaperone protein DnaJ [Escherichia coli APEC O1] DNAJ_ECOLC - Chaperone protein DnaJ OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=dnaJ PE=3 SV=1	6.0E-90	[19..377]	[1..344]
DNAJ_YERPA - Chaperone protein DnaJ OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=dnaJ PE=3 SV=1 gi\|166009061, gi... - gi\|166009061\|ref\|ZP_02229959.1\| chaperone protein DnaJ [Yersinia pestis biovar Antiqua str. E1979001... DNAJ_YERPN - Chaperone protein DnaJ OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=dnaJ PE=3 SV=1 gi\|165927315, gi... - gi\|165927315\|ref\|ZP_02223147.1\| chaperone protein DnaJ [Yersinia pestis biovar Orientalis str. F1991... gi\|167048930, gi... - gi\|167401548\|ref\|ZP_02307042.1\| chaperone protein DnaJ [Yersinia pestis biovar Antiqua str. UG05-045... gi\|166212081, gi... - gi\|166212081\|ref\|ZP_02238116.1\| chaperone protein DnaJ [Yersinia pestis biovar Antiqua str. B4200300... gi\|167054956, gi... - gi\|167426033\|ref\|ZP_02317786.1\| chaperone protein DnaJ [Yersinia pestis biovar Mediaevalis str. K197... gi\|166963234, gi... - gi\|167419240\|ref\|ZP_02310993.1\| chaperone protein DnaJ [Yersinia pestis biovar Orientalis str. MG05-... DNAJ_YERPB - Chaperone protein DnaJ OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=dnaJ PE=3 SV=1 gi\|89102681, gi\|... - gi\|89102681\|ref\|ZP_01175297.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_YERPY - Chaperone protein DnaJ OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=dnaJ PE=3 SV=1 DNAJ_YERPS - Chaperone protein DnaJ OS=Yersinia pseudotuberculosis GN=dnaJ PE=3 SV=1 DNAJ_YERPG - Chaperone protein DnaJ OS=Yersinia pestis bv. Antiqua (strain Angola) GN=dnaJ PE=3 SV=1 DNAJ_YERPE - Chaperone protein DnaJ OS=Yersinia pestis GN=dnaJ PE=3 SV=1 gi\|149289903, gi... - gi\|150260495\|ref\|ZP_01917223.1\| chaperone protein DnaJ [Yersinia pestis CA88-4125], gi\|149289903\|gb\|... gi\|229836948, gi... - gi\|229836948\|ref\|ZP_04457113.1\| chaperone Hsp40, co-chaperone with DnaK [Yersinia pestis Pestoides A... gi\|45438312, gi\|... - gi\|45443443\|ref\|NP_994982.1\| chaperone protein DnaJ [Yersinia pestis biovar Microtus str. 91001], gi... DNAJ_YERPP - Chaperone protein DnaJ OS=Yersinia pestis (strain Pestoides F) GN=dnaJ PE=3 SV=1 gi\|229696722, gi... - gi\|229840356\|ref\|ZP_04460515.1\| chaperone Hsp40, co-chaperone with DnaK [Yersinia pestis biovar Orie... gi\|21960686, gi\|... - gi\|22127579\|ref\|NP_671002.1\| chaperone protein DnaJ [Yersinia pestis KIM], gi\|21960686\|gb\|AAM87253.1... gi\|229842436, gi... - gi\|229842436\|ref\|ZP_04462591.1\| chaperone Hsp40, co-chaperone with DnaK [Yersinia pestis biovar Orie... gi\|16120798, gi\|... - gi\|218927666\|ref\|YP_002345541.1\| chaperone protein DnaJ [Yersinia pestis CO92], gi\|16120798\|ref\|NP_4... DNAJ_YERPS - Chaperone protein DnaJ OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=dnaJ PE=3 SV=1	9.0E-90	[19..377]	[1..347]
gi\|89106899, gi\|... - gi\|89106899\|ref\|AP_000679.1\| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli str. K-12 sub... DNAJ_ECODH - Chaperone protein DnaJ OS=Escherichia coli (strain K12 / DH10B) GN=dnaJ PE=3 SV=1 DNAJ_ECOLI - Chaperone protein dnaJ (Heat shock protein J) (HSP40) - Escherichia coli EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN... EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN...	1.0E-89	[19..377]	[1..344]
DNAJ_SHIF8 - Chaperone protein DnaJ OS=Shigella flexneri serotype 5b (strain 8401) GN=dnaJ PE=3 SV=1 gi\|30061585, gi\|... - gi\|30061585\|ref\|NP_835756.1\| chaperone protein DnaJ [Shigella flexneri 2a str. 2457T], gi\|30039827\|g...	1.0E-89	[19..377]	[1..344]
gi\|33578041 - gi\|33578041\|gb\|AAQ22347.1\| heat shock protein [Pseudomonas stutzeri A15] tr\|F8GZK8\|F8GZK8... - Chaperone protein DnaJ OS=Pseudomonas stutzeri (strain ATCC 17588 / DSM 5190 / CCUG 11256 / JCM 5965... DNAJ_PSEST - Chaperone protein DnaJ OS=Pseudomonas stutzeri GN=dnaJ PE=3 SV=1 tr\|F2N4J3\|F2N4J3... - Chaperone protein DnaJ OS=Pseudomonas stutzeri (strain DSM 4166 / CMT.9.A) GN=dnaJ PE=3 SV=1	1.0E-89	[19..376]	[1..347]
gi\|89256513, gi\|... - gi\|89256513\|ref\|YP_513875.1\| heat shock protein DnaJ [Francisella tularensis subsp. holarctica], gi\|... DNAJ_FRATU - Chaperone protein DnaJ OS=Francisella tularensis GN=dnaJ PE=3 SV=1 DNAJ_FRATH - Chaperone protein DnaJ OS=Francisella tularensis subsp. holarctica (strain LVS) GN=dnaJ PE=3 SV=1 gi\|167010479 - gi\|167010479\|ref\|ZP_02275410.1\| chaperone DnaJ [Francisella tularensis subsp. holarctica FSC200]	3.0E-89	[19..376]	[1..338]

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Predicted Domain #1

Region A:
Residues: [1-122]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPKLYIHLI LSLLLLPLIL AQDYYAILEI DKDATEKEIK SAYRQLSKKY HPDKNAGSEE  60
   61 AHQKFIEVGE AYDVLSDPEK KKIYDQFGAD AVKNGGGGGG PGGPGAGGFH DPFDIFERMF 120
  121 QG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.221849
Match:	1bq0__
Description:	DnaJ chaperone, N-terminal (J) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
unfolded protein binding	3.04403163860617	bayes_pls_golite062009
chaperone binding	2.86745334638583	bayes_pls_golite062009
binding	2.63138872417193	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
transcription regulator activity	1.91297632253219	bayes_pls_golite062009
nucleic acid binding	1.6342534817623	bayes_pls_golite062009
protein binding	1.60937254813642	bayes_pls_golite062009
DNA binding	1.55234338199368	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
transferase activity	0.240656521918556	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0276971914937192	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [123-377]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHGGPGGGFG QRQRQRGPMI KVQEKLSLKQ FYSGSSIEFT LNLNDECDAC HGSGSADGKL  60
   61 AQCPDCQGRG VIIQVLRMGI MTQQIQQMCG RCGGTGQIIK NECKTCHGKK VTKKNKFFHV 120
  121 DVPPGAPRNY MDTRVGEAEK GPDFDAGDLV IEFKEKDTEN MGYRRRGDNL YRTEVLSAAE 180
  181 ALYGGWQRTI EFLDENKPVK LSRPAHVVVS NGEVEVVKGF GMPKGSKGYG DLYIDYVVVM 240
  241 PKTFKSGQNM LKDEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.39794
Match:	1nltA_
Description:	The crystal structure of Hsp40 Ydj1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.7298921704023	bayes_pls_golite062009
protein disulfide isomerase activity	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	2.23398279564144	bayes_pls_golite062009
unfolded protein binding	2.04158808514315	bayes_pls_golite062009
protein binding	1.57926302986794	bayes_pls_golite062009
receptor binding	0.507762060964961	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: