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View Structure Prediction Details

Protein: BLM10
Organism: Saccharomyces cerevisiae
Length: 2143 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BLM10.

Description E-value Query
Range
Subject
Range
gi|32409989, gi|... - gi|32409989|ref|XP_325475.1| hypothetical protein [Neurospora crassa], gi|28921586|gb|EAA30880.1| hy...
gi|85095608 - gi|85095608|ref|XP_960116.1| hypothetical protein [Neurospora crassa OR74A]
0.0 [197..2134] [48..1946]
gi|46437612, gi|... - gi|68480080|ref|XP_715965.1| hypothetical protein CaO19.9728 [Candida albicans SC5314], gi|68479947|...
orf19.2182, orf1... - BLM3 CGDID:CAL0005443 Assembly 19, Contig19-10141 (45390, 38788) CDS, reverse complemented, translat...
0.0 [8..2142] [17..2199]
BLM10_YEAST - Proteasome activator BLM10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BLM10 PE=1 SV...
BLM10 - Proteasome activator subunit; found in association with core particles, with and without the 19S reg...
0.0 [1..2143] [1..2143]
gi|44985857, gi|... - gi|45201074|ref|NP_986644.1| AGL022Wp [Ashbya gossypii ATCC 10895], gi|44985857|gb|AAS54468.1| AGL02...
gi|44985857 - gi|44985857|gb|AAS54468.1| AGL022Wp [Ashbya gossypii ATCC 10895]
0.0 [5..2143] [2..2145]
gi|49096568, gi|... - gi|67538874|ref|XP_663211.1| hypothetical protein AN5607.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
0.0 [209..2143] [59..1968]
IPI:IPI00192488.... - Ensembl_locations(Chr-bp):14_random-3982016;14-102730670 TEMO, (NM_023986) TEMO [Rattus norvegicus]
gi|9954445, gi|4... - gi|9954445|gb|AAG09060.1|AF296169_1 TEMO [Mus musculus], gi|40556272|ref|NP_598774.1| proteasome (pr...
0.0 [1103..2143] [764..1803]
gi|85566853, gi|... - gi|85566853|gb|AAI12170.1| Proteasome (prosome, macropain) activator subunit 4 [Homo sapiens], gi|40...
0.0 [1103..2143] [690..1729]
gi|157762280 - gi|157762280|ref|XP_001673482.1| Hypothetical protein CBG08524 [Caenorhabditis briggsae AF16]
gi|39583853, gi|... - gi|39583853|emb|CAE63943.1| Hypothetical protein CBG08524 [Caenorhabditis briggsae], gi|187032580|em...
0.0 [1105..2142] [851..1902]

Back

Predicted Domain #1
Region A:
Residues: [1-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTANNDDDIK SPIPITNKTL SQLKRFERSP GRPSSSQGEI KRKKSRLYAA DGRPHSPLRA  60
   61 RSATPTLQDQ KLFNGMDSTS LLNERLQHYT LDYVSDRAQH MKNIYDPSSR WFSRSVRPEF 120
  121 PIEEFLPYKT ESHEDQAKYL CHVLVNLYIA ISSLDIQGLI SISSKDLADL KKEVDDLALK 180
  181 TDLFRLSNNT AENDLLGNDI ADYDDAEGLE DELDEYFDLA GPDFNATGKI 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [231-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAKSATIVNV NHWTNELKNC LHFDFPVALR KSLATVYYYL SLVQGQKVYR QMHVDMFERL  60
   61 VSLDDDRTNF 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [301-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TELLQKQGLL LDHQIMLNFL CEFLPYPDPD YARYELSSKE DLQLFRLLLK HAHNAKPFFD  60
   61 KSKESLLVDT MNFLLSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [378-449]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAPSTMMAVM PIVTSVVPYH YHIHSKIIDY FPFCYSIWSS VSANVAIDTH MYDFVGSISK  60
   61 DVHNKILSSE HE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [450-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDVVGVEFGE FGIFTDDQMT FMFNRLQGHL RTDGQIHSYS RTVKPFVYAI NGSKKDRFFE  60
   61 KLVSLAKAIE TFIHPSNNGF WTKPNAKFVH AFIKSYHGRV KYEED

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [555-707]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ICARGVTNGI CLTSFCHEEI VEIFLNIISL GSQNKNPDIA NYYISCFAYL LELDPSNAYL  60
   61 IYDKILIDLY DTLADQFINS RHRIISSLKQ FTRVIRFIVM DKLYRVHITN VLSMLVSKLD 120
  121 MNDTNLTSNL INGIVSIAAF IPIQDLTGED DYI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [708-856]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFESDTLPLV QQHFYHIKCG ESSKTFRVDD ELLNNAFKAS TTVFQSMLKV YVEKIFQLVD  60
   61 VDLEDSLVTK INQTTMILQE SMDDKIFNYF ASLLQRNFWS NDSFKEKDPN YELVTIPLAA 120
  121 LVRRNNGLSK ELVRTLLFHI KEQIKRGAG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [857-1034]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVRSTSEIQQ RDVKLVLYLT ALNDVLRQCH ESLLEYSDEL ITFMKYLYDN VTNPPLDVIT  60
   61 SIVIHSALAT LCTTEITDCR LFPEDSKIPE KDRWGGLQFD PRRFDKQHLS FQWHVPSSDE 120
  121 ITLSISILES LSEYCINNVE ELMKAPRHDS EYGDMIQKYV LVMTHTLSGS SLLFDPDF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1035-1165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKYRTQSNLS YREKLILLKN IRENNCDPQE LDIDIEQIRS GKDDEDYIES KDIEAGLNAG  60
   61 VSDVVQLRDE FPDELIVDEE VVSEMPSGVN TPIAGTHGTD NSAMSSDLAF RDLDIYTCNY 120
  121 YFGNTTEEKL Q

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1166-1328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPQYLQVHRV RARIGHFFHK LYVFLSTNFE NNTNMFQILL HGLKVWFTDL GQETVFNEDP  60
   61 NAFIDVDFLE NVQSLSHVNE PFTRTNFAIR ANSLHQSRVL LHSTNRKASK LENLLLVDII 120
  121 QLATSLYPDI YKPAQGTLVH CMKQLVGSYG VVINKIIPSL EKA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.96084803796407 bayes_pls_golite062009
hydrolase activity 2.62777210765927 bayes_pls_golite062009
nucleic acid binding 2.2915564382469 bayes_pls_golite062009
transcription regulator activity 1.78626120336243 bayes_pls_golite062009
DNA binding 1.62962293446832 bayes_pls_golite062009
protein binding 1.61131270705552 bayes_pls_golite062009
transcription factor activity 0.931585995872658 bayes_pls_golite062009
structural molecule activity 0.907636867485115 bayes_pls_golite062009
translation regulator activity 0.845133720454593 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.825554268911902 bayes_pls_golite062009
translation initiation factor activity 0.594620724124658 bayes_pls_golite062009
mRNA binding 0.328122666854777 bayes_pls_golite062009
RNA binding 0.243875756041061 bayes_pls_golite062009
transcription activator activity 0.005251231402011 bayes_pls_golite062009

Predicted Domain #11
Region A:
Residues: [1329-1412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKDHDYMKIQ VILNVLLIKK IHRKLMTDYK DIGRLIFLLI ECCRVNELEI GMYADKILTD  60
   61 IVIGIKIPSS VCVISDQAFL PLAP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1413-1588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDGTINLQVE AVKLAKKKKR EYYLSLLVDL QDKLLDKLDN EKDMGWKIRM FILRFVTQIQ  60
   61 SNLESKPDKR AVFSIISQIS TKHPEIIHLV VKSLLSTCNK IISLSDYEYD ITRAYKNEFN 120
  121 PSFVEILDTS TTSFPKTFTE EMNNFDNPKY FIDLRAYVGW LCWGRLMYVM SPKALK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #13
Region A:
Residues: [1589-1813]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNLRENELEV LKTAGHLLTR EFLRDVTMNL VQDNETRGVF SSGNVSFFSL VILLISSGFC  60
   61 ELNMSDLFEL CESYYNKDDK ASMIMSVEIV AGLVCGSKFM SVSDLDKRDT FIENFLAKCL 120
  121 DYELNHDAFE IWSTLAWWLP AVVDLRRSKT FFCHFINADG MFDRESDAAT HQTSKIYMLR 180
  181 SILMSMEFRA PDVGKLFDEL VFDHPYDQVR QAVAKLLTTL VQNQS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #14
Region A:
Residues: [1814-1982]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPSISDPTTL LEAERNDPDG LGLPLKSVPE KVDAYIKKQF EIIKNLEDSV VGLNPQQFIK  60
   61 TDYFYRTSTI FYWIKEMARG PNKVLLVPYL VDYVLPFLIG LVKHKDVCAL ASLDPVRLYA 120
  121 GLGYMPIRKN HVAAIVDYVC SSNVALSSNQ TKLQLAFIQH FLSAELLQL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #15
Region A:
Residues: [1983-2143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEEEKNKILE FVVSNLYNEQ FVEVRVRAAS ILSDIVHNWK EEQPLLSLIE RFAKGLDVNK  60
   61 YTSKERQKLS KTDIKIHGNV LGLGAIISAF PYVFPLPPWI PKQLSNLSSW ARTSGMTGQA 120
  121 AKNTISEFKK VRADTWKFDR ASFNTEELED LEGVLWRSYY A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle