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View Structure Prediction Details

Protein: VPS72
Organism: Saccharomyces cerevisiae
Length: 795 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS72.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
7.0E-54 [7..623] [842..1482]
MYH1_HORSE - Myosin-1 OS=Equus caballus GN=MYH1 PE=2 SV=1
2.0E-52 [7..623] [843..1483]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
3.0E-52 [7..619] [845..1481]
MYH2 - myosin, heavy chain 2, skeletal muscle, adult
4.0E-52 [7..619] [846..1482]
gi|14250231, gi|... - ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi|14250231|gb...
8.0E-52 [7..619] [847..1483]
MYSS_CYPCA - Myosin heavy chain, fast skeletal muscle OS=Cyprinus carpio PE=2 SV=2
4.0E-51 [7..623] [841..1481]

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Predicted Domain #1
Region A:
Residues: [1-365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDEGADKSL DTNTEFIIQT RSRRSNAGNK LQKLLEQELR DIESTKRQIS SYKNGNDDEE  60
   61 DEIGLLFQED EDDEDFEMMA KDDDDEGEEK EDETQSIRKE PSQASSEQAA DDLMFSSSES 120
  121 EDSSNENDED AEEKEIRRQE LLSRKKRNKR LQKGPVVIKK QKPKPKSGEA IPRSHHTHEQ 180
  181 LNAETLLLNT RRTSKRSSVM ENTMKVYEKL SKAEKKRKII QERIRKHKEQ ESQHMLTQEE 240
  241 RLRIAKETEK LNILSLDKFK EQEVWKKENR LALQKRQKQK FQPNETILQF LSTAWLMTPA 300
  301 MELEDRKYWQ EQLNKRDKKK KKYPRKPKKN LNLGKQDASD DKKRESEESI KNDGDVNSLG 360
  361 ENSSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [366-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHNQKRIEET STNDTVEGES SPDAAVSRVN SDELKPTALP DVTLDAIANK QSTVDEAPNS  60
   61 QPQKNIITNE QKITNVGEPI QNLHNEEIKD EMVSALESRE NTFENSSPAA QVVSQRDNSA 120
  121 TPTPSNSTGT EDTILISPDT DIKGEPEPCL KTEGIENLSH NVPQETKSNT DVSFLKQVTF 180
  181 TDHPQVAIID TEESPSKKDT ANVDESSAEN SLSTQTYEGP EQLTSRNFVT LYDFPNAPPN 240
  241 LKDFNTNLFG DRWSYTNG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [624-795]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSATQRPQDM KTVFHSILPS PPQSSVPSPT VDISLDLSAL ANFPSFGEYD KKIVHQINTE  60
   61 INKDLEIKIK TQPPTGVFLA NGIRKKCLIT NKECQYFDPR TGVPYSDVEA YKIIQRIQDP 120
  121 ISKEEGRSDI KRDETTNEDS DDQVRFKWFG FKNGGIYLDL SQRPAKGVPE GF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle