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View Structure Prediction Details

Protein: UBP14
Organism: Saccharomyces cerevisiae
Length: 781 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBP14.

Description E-value Query
Range
Subject
Range
UBP14 - Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in ...
UBP14_YEAST - Ubiquitin carboxyl-terminal hydrolase 14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
0.0 [1..781] [1..781]
gi|60652821, gi|... - gi|60652821|gb|AAX29105.1| ubiquitin specific protease 5 [synthetic construct], gi|30583883|gb|AAP36...
0.0 [2..780] [9..832]
gi|1732411, gi|1... - gi|1732411|gb|AAB51314.1| isopeptidase T [Homo sapiens], gi|148727247|ref|NP_003472.2| ubiquitin spe...
gi|123999428, gi... - gi|123999428|gb|ABM87273.1| ubiquitin specific peptidase 5 (isopeptidase T) [synthetic construct], g...
0.0 [2..780] [9..832]
gi|109474195, gi... - gi|34858442|ref|XP_238380.2| PREDICTED: similar to Ubiquitin carboxyl-terminal hydrolase 5 (Ubiquiti...
0.0 [2..780] [9..855]
UBP5_MOUSE - Ubiquitin carboxyl-terminal hydrolase 5 OS=Mus musculus GN=Usp5 PE=1 SV=1
0.0 [2..780] [9..855]
gi|36939185 - gi|36939185|gb|AAQ86957.1| isopeptidase T [Xenopus laevis]
0.0 [2..780] [7..851]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEAVLENVN VPAVVSKDEC IYCFESPYNE PLALNASPKH SLNICLNCFQ ATCNRHVPLH  60
   61 IRVTEYACDT IHSNYLTIAK VEKPKQENVE ENNNNKKIKL QVIETSEDDT HNTIWSLQRF 120
  121 NGENVPRTVL SKSTDSDIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [140-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STALEKIEKI LKAKSQDFED KKNSWVLEIS TCPHTENFQI PSKPENTVNL NQCSSCDLTQ  60
   61 NLWLCLHCGN IGCGREQIGI DGHSHALDHY RSNNNHPLAI KLGSLSSSTY DLYCYACDDE 120
  121 TRFPDNVNLG SALQIYGINI QEKIADEKTL VQLQVE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 30.387216
Match: PF02148.6
Description: No description for PF02148.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [296-700]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNENWQFRMV DSSGKEFEKL SASKNYGCGL INLGNSCYLN SVIQSLVNGG VPNWSLDFLG  60
   61 SKFPLDVVYP DNNLKCQWIK LLNAMKCEPE LYPNGIKPTT FKKCIGQNHQ EFSSNRQQDA 120
  121 MEFLTFLLDL LDKKFFSSSS SGIPNPNDLV RFMMEDRLQC NICGKVKYSY EPTEAIQIPL 180
  181 EENDEPQDML ERIKAYFEGQ TIEFKCANCK EKVTANKKPG FKSLPQTLIL NPIRIRLQNW 240
  241 IPVKTSNELS LPGLIDRDDM LDVSSYLSQG FDPQTENLLP DEDENRSSFT PNQCSISQLI 300
  301 EMGFTQNASV RALFNTGNQD AESAMNWLFQ HMDDPDLNDP FVPPPNVPKK DKREVDEVSL 360
  361 TSMLSMGLNP NLCRKALILN NGDVNRSVEW VFNNMDDDGT FPEPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.522879
Match: 1nbfA_
Description: Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [701-781]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPNEEQQQKK DLGYSTAKPY ALTAVICHKG NSVHSGHYVV FIRKLVADKW KWVLYNDEKL  60
   61 VAADSIEDMK KNGYIYFYTR C

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle