YRC Public Data Repository - Protein Structure Prediction

Protein:	YVC1
Organism:	Saccharomyces cerevisiae
Length:	675 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YVC1.

Description	E-value	Query Range	Subject Range
YVC1_YEAST - Calcium channel YVC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YVC1 PE=1 SV=2 YVC1 - Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic sho...	0.0	[1..675]	[1..675]
gi\|16517172, gi\|... - gi\|6665592\|gb\|AAF22928.1\|AF063823_1 trp-related protein 4 truncated variant beta [Homo sapiens], gi\|... gi\|114649431 - gi\|114649431\|ref\|XP_001148772.1\| PREDICTED: transient receptor potential 4 isoform 4 [Pan troglodyte...	3.0E-95	[8..675]	[118..829]
gi\|46116672, gi\|... - gi\|46116672\|ref\|XP_384354.1\| hypothetical protein FG04178.1 [Gibberella zeae PH-1], gi\|42547922\|gb\|E...	2.0E-88	[10..667]	[24..668]
TRPC4_BOVIN, TRP... - Short transient receptor potential channel 4 OS=Bos taurus GN=TRPC4 PE=2 SV=1, (P79100) Short transi...	3.0E-88	[8..654]	[120..812]
gi\|10697342 - gi\|10697342\|gb\|AAG21810.1\|AF288408_1 transient receptor potential Trp4beta [Rattus norvegicus]	7.0E-88	[8..675]	[118..828]
gi\|2935630, gi\|4... - gi\|4200419\|gb\|AAD10168.1\| putative capacitative calcium entry channel Trp4 [Mus musculus], gi\|293563...	2.0E-87	[8..675]	[118..825]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSANGDLHL PISNEQCMPE NNGSLGFEAP TPRQILRVTL NLKYLIDKVV PIVYDPNDIV  60
   61 CDHSEILSPK VVKLAYEACG GNPKDKANKR KYQSVIIFSL LKVCEWYSIL ATMEVHNAKL 120
  121 YETRNLASQQ LCKLLIEREE TRDLQFLFMQ LLLRRYVINE NDEDQEPLNA LELATDMHCT 180
  181 TVIGSSGFQR CLKWIWRGWI VQNGLDPTTF IKDDSL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [217-490]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEVSLISHFN PVRLKAPVYQ NYLQMIFSFL FLGLYTLVVN GKDSERVQSF DLLESIFYVF  60
   61 NTGFILDELT KLYYIGYAHL SFWNLFNDTT YLIITFAMGF RAMSVTPLNA KYSSEDWDKI 120
  121 SYRVLSCAAP FVWSRLLLYL ESQRFIGIML VILKHMMKES IVFFFLLFLI MIGFTQGFLG 180
  181 LDSADGKRDI TGPILGNLTI TVLGLGSFDV FEEFAPPYAA ILYYGYYFIV SVILLNILIA 240
  241 LYSTAYQKVI DNADDEYMAL MSQKTLRYIR APDE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.69897
Match:	1orqC_
Description:	Potassium channel KVAP
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [491-675]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVYVSPLNLI EVFMTPIFRI LPPKRAKDLS YTVMTIVYSP FLLLISVKET REARRIKYNR  60
   61 MKRLNDDANE YDTPWDLTDG YLDDDDGLFS DNRNSGMRAT QLKNSRSLKL QRTAEQEDVH 120
  121 FKVPKKWYKN VKKCSPSFEQ YDNDDTEDDA GEDKDEVKEL TKKVENLTAV ITDLLEKLDI 180
  181 KDKKE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits