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View Structure Prediction Details

Protein: HDA3
Organism: Saccharomyces cerevisiae
Length: 655 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HDA3.

Description E-value Query
Range
Subject
Range
gi|8250661 - gi|8250661|gb|AAB29713.2| myosin heavy chain [Rattus sp.]
3.0E-64 [10..654] [207..844]
MYH1_BOVIN - Myosin-1 OS=Bos taurus GN=MYH1 PE=2 SV=2
6.0E-64 [33..654] [1276..1890]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
8.0E-64 [33..654] [1277..1891]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
9.0E-64 [33..655] [292..907]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
9.0E-64 [33..655] [1281..1896]
MYH1_PIG - Myosin-1 OS=Sus scrofa GN=MYH1 PE=2 SV=1
9.0E-64 [10..654] [1254..1891]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
1.0E-63 [10..654] [1253..1890]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLLRILDTK PIPTIVDATT LGISGNTSGD YWLPTTMSLY QKELTDQIVS LHYSDILRYF  60
   61 ETSHYKEDVI LESMKTMCLN GSLVATHPYL LIDHYMPKSL ITRDVPAHLA ENSGKFSVLR 120
  121 DLINLVQEYE TETAIVCRPG RTMDLLEALL LGNKVHIKRY DGHSIKSKQK ANDFSCTVHL 180
  181 FSSEGINFTK YPIKSKARFD MLICLDTTVD TSQKDIQYLL QYKRERKGLE RYAPIVRLVA 240
  241 I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 2mysA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [242-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSIDHCRLFF GKKFDKNSRE YLENVTAAMV ILRDRLGTLP PDLRPIYSQK LHYLVEWLEN  60
   61 PTVPWPLPDI YPLKQYTSMD VERSLLTEVH FKKSDDQLED AFSNCSKKRG RHGANKAASS 120
  121 T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [363-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAGIEDNITP SFYSTKRLKN DYYTNPLKQD MTQLTGITTA DNSSNVNYHL SSGIITHKLI  60
   61 QSMG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.221849
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [427-655]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVYMDICVQK QELDDYSCLD DLQNDHLKFF SNEDEKIIKE YETVLRTNNE NLNRSHELEV  60
   61 ENNLKFSQIE TLEKDIETLK GSLMAQGETL SKLKDAFVKT DNVQDEIEKE ERVSVSRDTE 120
  121 KKYMEQEIKR AVDAIRENEE ETHKLNEKQN GLESELKLKF EKSEISTKEL NEKIGFLKKE 180
  181 LKLENDLNEE LVGQLSKTMD NLENLTIPRV RTQNGNTKKK SRAKKPGNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.221849
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle