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View Structure Prediction Details

Protein: HDA3
Organism: Saccharomyces cerevisiae
Length: 655 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HDA3.

Description E-value Query
Range
Subject
Range
gi|8250661 - gi|8250661|gb|AAB29713.2| myosin heavy chain [Rattus sp.]
3.0E-64 [10..654] [207..844]
MYH1_BOVIN - Myosin-1 OS=Bos taurus GN=MYH1 PE=2 SV=2
6.0E-64 [33..654] [1276..1890]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
8.0E-64 [33..654] [1277..1891]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
9.0E-64 [33..655] [292..907]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
9.0E-64 [33..655] [1281..1896]
MYH1_PIG - Myosin-1 OS=Sus scrofa GN=MYH1 PE=2 SV=1
9.0E-64 [10..654] [1254..1891]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
1.0E-63 [10..654] [1253..1890]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLLRILDTK PIPTIVDATT LGISGNTSGD YWLPTTMSLY QKELTDQIVS LHYSDILRYF  60
   61 ETSHYKEDVI LESMKTMCLN GSLVATHPYL LIDHYMPKSL ITRDVPAHLA ENSGKFSVLR 120
  121 DLINLVQEYE TETAIVCRPG RTMDLLEALL LGNKVHIKRY DGHSIKSKQK ANDFSCTVHL 180
  181 FSSEGINFTK YPIKSKARFD MLICLDTTVD TSQKDIQYLL QYKRERKGLE RYAPIVRLVA 240
  241 I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 2mysA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [242-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSIDHCRLFF GKKFDKNSRE YLENVTAAMV ILRDRLGTLP PDLRPIYSQK LHYLVEWLEN  60
   61 PTVPWPLPDI YPLKQYTSMD VERSLLTEVH FKKSDDQLED AFSNCSKKRG RHGANKAASS 120
  121 T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.410 d.95.2 Homing endonucleases
View Download 0.415 a.66.1 Transducin (alpha subunit), insertion domain
View Download 0.372 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.415 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.566 d.52.2 GMP synthetase C-terminal dimerisation domain
View Download 0.318 a.185.1 Gametocyte protein Pfg27
View Download 0.297 a.74.1 Cyclin-like
View Download 0.280 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.274 c.110.1 D-Tyr tRNAtyr deacylase, DTD
View Download 0.272 a.24.4 Hemerythrin
View Download 0.261 a.1.1 Globin-like
View Download 0.260 a.47.2 t-snare proteins
View Download 0.255 a.24.17 Group V grass pollen allergen
View Download 0.246 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.236 a.7.6 Ribosomal protein S20
View Download 0.230 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.228 a.26.1 4-helical cytokines
View Download 0.225 c.47.1 Thioredoxin-like
View Download 0.217 a.118.9 ENTH/VHS domain
View Download 0.216 a.19.1 Fertilization protein
View Download 0.213 a.2.3 Chaperone J-domain
View Download 0.211 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.210 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.208 a.75.1 Ribosomal protein S7
View Download 0.207 a.142.1 PTS-regulatory domain, PRD
View Download 0.205 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.204 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.202 a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.201 d.110.2 GAF domain-like

Predicted Domain #3
Region A:
Residues: [363-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAGIEDNITP SFYSTKRLKN DYYTNPLKQD MTQLTGITTA DNSSNVNYHL SSGIITHKLI  60
   61 QSMG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.221849
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [427-655]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVYMDICVQK QELDDYSCLD DLQNDHLKFF SNEDEKIIKE YETVLRTNNE NLNRSHELEV  60
   61 ENNLKFSQIE TLEKDIETLK GSLMAQGETL SKLKDAFVKT DNVQDEIEKE ERVSVSRDTE 120
  121 KKYMEQEIKR AVDAIRENEE ETHKLNEKQN GLESELKLKF EKSEISTKEL NEKIGFLKKE 180
  181 LKLENDLNEE LVGQLSKTMD NLENLTIPRV RTQNGNTKKK SRAKKPGNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.221849
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle