YRC Public Data Repository - Protein Structure Prediction

Protein:	YPR147C
Organism:	Saccharomyces cerevisiae
Length:	304 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPR147C.

Description	E-value	Query Range	Subject Range
YP147_YEAST - Uncharacterized protein YPR147C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPR147C ... YPR147C - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... gi\|190408070 - gi\|190408070\|gb\|EDV11335.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]	0.0	[1..304]	[1..304]
LDAH_MOUSE - Lipid droplet-associated hydrolase OS=Mus musculus GN=Ldah PE=1 SV=1	7.0E-89	[11..297]	[21..309]
CG9186-PB, CG9186-PA - This gene is referred to in FlyBase by the symbol Dmel\CG9186 (CG9186, FBgn0035206). It is a protein... gi\|220946882, gi... - gi\|220956420\|gb\|ACL90753.1\| CG9186-PA [synthetic construct], gi\|220946882\|gb\|ACL85984.1\| CG9186-PA [...	2.0E-82	[11..297]	[11..291]
C2orf43 - chromosome 2 open reading frame 43	2.0E-82	[12..297]	[22..308]
gi\|21536959 - gi\|21536959\|gb\|AAM61300.1\| unknown [Arabidopsis thaliana]	2.0E-80	[4..261]	[12..261]
CE20724 - status:Confirmed UniProt:Q93595 protein_id:CAB01705.1	5.0E-70	[24..297]	[16..295]
gi\|32420089, gi\|... - gi\|32420089\|ref\|XP_330488.1\| predicted protein [Neurospora crassa], gi\|28919220\|gb\|EAA28700.1\| predi... gi\|85089403 - gi\|85089403\|ref\|XP_957936.1\| hypothetical protein NCU09838 [Neurospora crassa OR74A]	2.0E-45	[31..297]	[52..414]

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Predicted Domain #1

Region A:
Residues: [1-118]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVKEYTKSK LPCSILNIKP TVTKSGEDAP LLVWIPGNPG LLYYYQEMLH HLHLKHPDWE  60
   61 ILGISHAGMT LNAHSNTPIF SLQDQVDHQV EVINNFSCKN RKIIIMGHSV GAYIVQKV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.689	0.825	cytoplasm	c.37.1	P-loop containing nucleoside triphosphate hydrolases

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.531942688196759	bayes_pls_golite062009
hydrolase activity	0.464324757821572	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [119-304]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CLSNKLVGSV QKVGLVTPTV MDIHTSEMGI KMTAALRYIP PLAHVVSLFS YIFFYWILSE  60
   61 GFSRFIIDKF MGCGSTGYQA VLSTRIFLTH RQFVRQSLGL AAQEMEEITT NWEFQDRFIN 120
  121 YCEENGISIW FLFSSNDHWV SGKTRSHLSD YYKDKVKQER LKIDVTDKIP HSFVVKHAEY 180
  181 AINAFF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: