YRC Public Data Repository - Protein Structure Prediction

Protein:	NOC4
Organism:	Saccharomyces cerevisiae
Length:	552 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NOC4.

Description	E-value	Query Range	Subject Range
gi\|190408067 - gi\|190408067\|gb\|EDV11332.1\| nucleolar complex protein 4 [Saccharomyces cerevisiae RM11-1a] gi\|207340257 - gi\|207340257\|gb\|EDZ68663.1\| YPR144Cp-like protein [Saccharomyces cerevisiae AWRI1631] NOC4_YEAST - Nucleolar complex protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOC4 PE=1 SV... NOC4 - Nucleolar protein, forms a complex with Nop14p that mediates maturation and nuclear export of 40S ri... gi\|151942916 - gi\|151942916\|gb\|EDN61262.1\| U3 snoRNP protein [Saccharomyces cerevisiae YJM789]	0.0	[1..552]	[1..552]
gi\|18086412 - gi\|18086412\|gb\|AAL57663.1\| At2g17250/T23A1.11 [Arabidopsis thaliana]	0.0	[4..534]	[16..562]
gi\|19354321, gi\|... - gi\|74186323\|dbj\|BAE42938.1\| unnamed protein product [Mus musculus], gi\|19354321\|gb\|AAH24616.1\| Nucle...	0.0	[6..523]	[9..495]
NOC4L - nucleolar complex associated 4 homolog (S. cerevisiae) gi\|123983406, gi... - gi\|123998109\|gb\|ABM86656.1\| nucleolar complex associated 4 homolog (S. cerevisiae) [synthetic constr...	0.0	[7..523]	[10..495]
gi\|220951730 - gi\|220951730\|gb\|ACL88408.1\| CG2875-PA [synthetic construct] CG2875-PA - This gene is referred to in FlyBase by the symbol Dmel\CG2875 (CG2875, FBgn0029672). It is a protein...	0.0	[3..529]	[4..482]
SPBC1604.06c - CBF /Mak21 family YG06_SCHPO - Uncharacterized protein C1604.06c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC1604...	0.0	[8..527]	[2..475]
NOC3L_CRIGR - Nucleolar complex protein 3 homolog OS=Cricetulus griseus GN=NOC3L PE=2 SV=1	7.0E-88	[32..525]	[232..754]

Back

Predicted Domain #1

Region A:
Residues: [1-425]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLLISEIKD IAKRLTAAGD RKQYNSIIKL INELVIPENV TQLEEDETEK NLRFLVMSLF  60
   61 QIFRKLFSRG DLTLPSSKKS TLEKEQFVNW CRKVYEAFKT KLLAIISDIP FETSLGLDSL 120
  121 DVYLQLAELE STHFASEKGA PFFPNKTFRK LIIALWSSNM GEIEDVKSSG ASENLIIVEF 180
  181 TEKYYTKFAD IQYYFQSEFN QLLEDPAYQD LLLKNVGKWL ALVNHDKHCS SVDADLEIFV 240
  241 PNPPQAIENE SKFKSNFEKN WLSLLNGQLS LQQYKSILLI LHKRIIPHFH TPTKLMDFLT 300
  301 DSYNLQSSNK NAGVVPILAL NGLFELMKRF NLEYPNFYMK LYQIINPDLM HVKYRARFFR 360
  361 LMDVFLSSTH LSAHLVASFI KKLARLTLES PPSAIVTVIP FIYNLIRKHP NCMIMLHNPA 420
  421 FISNP

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	9.09
Match:	1b3uA_
Description:	Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [426-552]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQTPDQVANL KTLKENYVDP FDVHESDPEL THALDSSLWE LASLMEHYHP NVATLAKIFA  60
   61 QPFKKLSYNM EDFLDWNYDS LLNAESSRKL KTLPTLEFEA FTNVFDNEDG DSEASSQGNV 120
  121 YLPGVAW

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits