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View Structure Prediction Details

Protein: CLB5
Organism: Saccharomyces cerevisiae
Length: 435 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLB5.

Description E-value Query
Range		 Subject
Range
CGB1_CRILO - (Q08301) G2/mitotic-specific cyclin B1
CCNB1_CRIGR - G2/mitotic-specific cyclin-B1 OS=Cricetulus griseus GN=CCNB1 PE=2 SV=1
 0.0 [8..421] [2..417]
gi|254022 - gi|254022|gb|AAB22970.1| cyclin B1 [Mus sp.]
CCNB1_MOUSE - G2/mitotic-specific cyclin-B1 OS=Mus musculus GN=Ccnb1 PE=1 SV=3
 0.0 [8..421] [2..418]
CCNB1_MESAU - G2/mitotic-specific cyclin-B1 OS=Mesocricetus auratus GN=CCNB1 PE=2 SV=1
 0.0 [8..421] [2..417]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [8..421] [2..418]
CCNB1, CGB1 - chorionic gonadotropin, beta polypeptide 1, cyclin B1
gi|123990181 - gi|123990181|gb|ABM83901.1| cyclin B1 [synthetic construct]
 0.0 [8..417] [2..417]
CCNB1_RAT - G2/mitotic-specific cyclin-B1 OS=Rattus norvegicus GN=Ccnb1 PE=2 SV=1
 0.0 [8..421] [2..411]
CGS5_YEAST - S-phase entry cyclin-5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLB5 PE=1 SV=1
gi|151942897 - gi|151942897|gb|EDN61243.1| B-type cyclin [Saccharomyces cerevisiae YJM789]
gi|190408047 - gi|190408047|gb|EDV11312.1| S-phase entry cyclin-5 [Saccharomyces cerevisiae RM11-1a]
CLB5 - B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of ...
 0.0 [1..435] [1..435]
gi|147906017, gi... - gi|27735397|gb|AAH41302.1| Ccnb1-prov protein [Xenopus laevis], gi|147906017|ref|NP_001080196.1| cyc...
 0.0 [8..419] [2..385]
CCNB2_RANJA - G2/mitotic-specific cyclin-B2 OS=Rana japonica GN=CCNB2 PE=2 SV=1
 0.0 [29..421] [2..380]

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Predicted Domain #1
Region A:
Residues: [1-137] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGENHDHEQS IKRNSMIYNE NERQLCNSNL KILQNKRALS KNDSSSKQQV QDSKPRRALT  60
   61 DVPVNNNPLS QNKRIVAGSK AAKVRREENI RPIVSAVQKR QIYNDRTAAE QEEEEEEEGE 120
  121 DDDAASIVNK KRRIDAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [138-172] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVSEIVGWQD LDYVEKDDTA MVAEYSAEIF AFLYR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [298-435] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLNFLRRISK ADDYDPVNRN IGKFILEYAY CCHQFIHLPP STVSAMAMYI ARRMTNRNKN  60
   61 ELWNGTLQHY SGGIDPIHDE AFQSLCIDLV KDIASSKTHL DSLILKYKKP RYGSVYFQTF 120
  121 KWCTSEMHSN FQNLFNLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 295.232149
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [173-297] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RELETLPSHN YLLDKTSKYY LRPSMRTILV DWLVEVHEKF QCYPETLFLS INLMDRFLAK  60
   61 NKVTMNKLQL LAVTSLFIAA KFEEVNLPKL AEYAYITDGA ASKNDIKNAE MFMLTSLEFN 120
  121 IGWPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 295.232149
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle