YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: COG4
Organism: Saccharomyces cerevisiae
Length: 861 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COG4.

Description E-value Query
Range
Subject
Range
COG4_YEAST - Conserved oligomeric Golgi complex subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
gi|207340292 - gi|207340292|gb|EDZ68686.1| YPR105Cp-like protein [Saccharomyces cerevisiae AWRI1631]
COG4 - Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tet...
0.0 [1..861] [1..861]
gi|21070956, gi|... - gi|21070956|ref|NP_056201.1| component of oligomeric golgi complex 4 [Homo sapiens], gi|10434521|dbj...
0.0 [26..858] [29..774]
COG4_MOUSE - Conserved oligomeric Golgi complex subunit 4 OS=Mus musculus GN=Cog4 PE=1 SV=1
0.0 [26..858] [29..774]
gi|220955786, gi... - gi|220955786|gb|ACL90436.1| CG7456-PA [synthetic construct], gi|220946112|gb|ACL85599.1| CG7456-PA [...
CG7456-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7456 (CG7456, FBgn0032258). It is a protein...
0.0 [23..858] [4..765]
cogc-4 - status:Partially_confirmed UniProt:Q95XZ0 protein_id:AAK39338.1
0.0 [20..858] [18..791]
gi|15234170, gi|... - gi|7267637|emb|CAB80949.1| hypothetical protein [Arabidopsis thaliana], pir||C85018 hypothetical pro...
0.0 [65..858] [429..1106]

Back

Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGQKSNASW ESSIIEGQLS KNLARYTLLL DKLSTLSQID KLSEVIANDY AKQSKQLNAF  60
   61 VQQSQSSLNK ESRKLELQRT NLTTTLTQFH ETVATISSSN ARAKAIHDDI ETVDQERALV 120
  121 NKTLQFVKDV RTLKNNISLA HSALETKDYL VAATAINEIR SLPDKKLIVS EFAKKVVPSS 180
  181 EIPEEPAILI KNWCKELTSL FQEQFMEATR TQDIKELTLM FKMFPMIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.522879
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [229-558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDVLGLDLYS KYVCDIIADE SRKIMSNSME NSTKFQGFFS QVLLHLFKIV STIINDHSKV  60
   61 IATCYGKKHM VHVMEKVEKE ADLQASLILD IFMETRKIER TIHDINEWEH SQKNEDVNID 120
  121 SNQSDIETDG ETEKSSIISI HDLALLIMEF SQILQNWSMY SRFYSVKWNE FSDLHPHVLQ 180
  181 PPPPIADGKF ALKLKQDKVF DEFQVFVLNH LQRSFRNSIS LEELPSLNDL ITAVPLNDHD 240
  241 NISYPVTSVL DDLILLVRKN LISVVNTGQF KLLASFLNEL VKFFQNRFLV KFMQNKFKLL 300
  301 QSKLASNVSL KRYIPKGEEQ SATSRSVSPP 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [559-861]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANKFSPLSRF TFRGAAASAL TNIQSNLQAV VAEDEDSILA LHHYLIYLNT LYLSKVYVHR  60
   61 LLSIEILEDD SQRILRDNFP FDNDAAQLQN LIINSEKLVL EQTDKLSKWA VKYLFQNILQ 120
  121 NRVRNLLGTV FVNSASSNSS TSNQKNVSRD YSAGSNQKNY ITSIEDFEDL SQINSFNSKW 180
  181 NQLIIPYKNI LHNEAYAELL SVIVDYIVTT LEQRIWTLEF NELGVTKLDR ELSLFIGNMC 240
  241 GLNYNLREKF LKLTQIVLLL GLDDDNFDLT TGDIKDDFNG TFDWVINSQE RIKARNMKID 300
  301 RTQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle