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View Structure Prediction Details

Protein: PRE2
Organism: Saccharomyces cerevisiae
Length: 287 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRE2.

Description E-value Query
Range
Subject
Range
gi|151942879 - gi|151942879|gb|EDN61225.1| proteasome subunit [Saccharomyces cerevisiae YJM789]
PSB5_YEAST - Proteasome subunit beta type-5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRE2 PE=1...
gi|190408030 - gi|190408030|gb|EDV11295.1| proteasome subunit [Saccharomyces cerevisiae RM11-1a]
PRE2 - Beta 5 subunit of the 20S proteasome, responsible for the chymotryptic activity of the proteasome
7.0E-81 [1..287] [1..287]
gi|18157533 - gi|18157533|dbj|BAB83848.1| PSMB8-A [Oryzias latipes]
8.0E-73 [30..277] [29..272]
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1
PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1
2.0E-72 [46..272] [4..234]
gi|4545092, gi|4... - gi|47522620|ref|NP_999100.1| proteasome beta 8 subunit [Sus scrofa], gi|4545092|gb|AAD22390.1|AF0594...
6.0E-72 [31..277] [13..257]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-71 [3..280] [4..278]
PSA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC ...
PSMA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii GN=psmA PE=3 SV=1
2.0E-71 [46..273] [4..235]
PSB8_RAT - Proteasome subunit beta type-8 OS=Rattus norvegicus GN=Psmb8 PE=1 SV=3
6.0E-71 [31..277] [24..268]
gi|972988, gi|97... - gi|972988|gb|AAA75036.1| 20S proteasome subunit Lmp7 [Mus musculus], gi|972986|gb|AAA75035.1| 20S pr...
6.0E-71 [31..277] [29..273]
gi|18124203 - gi|18124203|gb|AAL59862.1|AF363583_1 proteasome beta-subunit LMP7 [Heterodontus francisci]
6.0E-71 [26..280] [21..272]

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Predicted Domain #1
Region A:
Residues: [1-65]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAIADSFSV PNRLVKELQY DNEQNLESDF VTGASQFQRL APSLTVPPIA SPQQFLRAHT  60
   61 DDSRN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [66-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDCKIKIAHG TTTLAFRFQG GIIVAVDSRA TAGNWVASQT VKKVIEINPF LLGTMAGGAA  60
   61 DCQFWETWLG SQCRLHELRE KERISVAAAS KILSNLVYQY KGAGLSMGTM ICGYTRKEGP 120
  121 TIYYVDSDGT RLKGDIFCVG SGQTFAYGVL DSNYKWDLSV EDALYLGKRS ILAAAHRDAY 180
  181 SGGSVNLYHV TEDGWIYHGN HDVGELFWKV KEEEGSFNNV IG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1302.69897
Match: 1g0uK_
Description: Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle