YRC Public Data Repository - Protein Structure Prediction

Protein:	UBA3
Organism:	Saccharomyces cerevisiae
Length:	299 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBA3.

Description	E-value	Query Range	Subject Range
gi\|50401616, gi\|... - sp\|Q8TBC4\|UB1C_HUMAN Ubiquitin-activating enzyme E1C (Nedd8-activating enzyme E1C) (Ubiquitin-activa... gi\|123992983, gi... - gi\|123999911\|gb\|ABM87464.1\| ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) [synthetic constru...	2.0E-73	[3..299]	[70..373]
UBA3_RAT - NEDD8-activating enzyme E1 catalytic subunit OS=Rattus norvegicus GN=Uba3 PE=1 SV=1	2.0E-73	[3..299]	[70..373]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	4.0E-73	[3..299]	[75..378]
UBA3_MOUSE, UB1C... - NEDD8-activating enzyme E1 catalytic subunit OS=Mus musculus GN=Uba3 PE=2 SV=1, (Q8C878) Ubiquitin-a...	4.0E-73	[3..299]	[70..373]
UBA3_DANRE - NEDD8-activating enzyme E1 catalytic subunit OS=Danio rerio GN=uba3 PE=2 SV=1	2.0E-69	[3..299]	[69..372]
gi\|32422575, gi\|... - gi\|32422575\|ref\|XP_331731.1\| hypothetical protein [Neurospora crassa], gi\|28927475\|gb\|EAA36427.1\| NE... gi\|85119569 - gi\|85119569\|ref\|XP_965663.1\| NEDD8-activating enzyme E1 catalytic subunit [Neurospora crassa OR74A]	3.0E-67	[4..296]	[45..344]
CG13343-PA - This gene is referred to in FlyBase by the symbol Dmel\CG13343 (CG13343, FBgn0033882). It is a prote...	3.0E-66	[2..298]	[48..350]
gi\|1814236 - gi\|1814236\|gb\|AAB41850.1\| ubiquitin-activating enzyme	6.0E-66	[4..295]	[38..338]

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Predicted Domain #1

Region A:
Residues: [1-103]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDCKILVLGA GGLGCEILKN LTMLSFVKQV HIVDIDTIEL TNLNRQFLFC DKDIGKPKAQ  60
   61 VAAQYVNTRF PQLEVVAHVQ DLTTLPPSFY KDFQFIISGL DAI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [126-143]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPFIDGGTEG LKGHVKTI

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [234-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPSVSTTNAM VAATCCTQMV KIYNDLIDLE NGNNFTLINC SEGCFMYSFK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	756.264245
Match:	1ngvB_
Description:	UBA3

Predicted Domain #2

Region A:
Residues: [104-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPRRFINETL VKLTLESNYE IC

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [144-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPGITACWEC SIDTLPSQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [284-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FERLPDCTVC SNSNSN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	756.264245
Match:	1ngvB_
Description:	UBA3

Predicted Domain #3

Region A:
Residues: [162-233]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDTVPMCTIA NNPRCIEHVV EYVSTIQYPD LNIESTADME FLLEKCCERA AQFSISTEKL  60
   61 STSFILGIIK SI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	756.264245
Match:	1ngvB_
Description:	UBA3

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits