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View Structure Prediction Details

Protein: SMK1
Organism: Saccharomyces cerevisiae
Length: 388 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMK1.

Description E-value Query
Range
Subject
Range
MPK4_ARATH - Mitogen-activated protein kinase 4 OS=Arabidopsis thaliana GN=MPK4 PE=1 SV=2
0.0 [3..382] [8..373]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [3..382] [8..373]
MMK1_MEDSA - Mitogen-activated protein kinase homolog MMK1 OS=Medicago sativa GN=MMK1 PE=1 SV=1
0.0 [11..384] [28..386]
gi|25052804 - gi|25052804|gb|AAN65180.1| mitogen-activated protein kinase 4 [Petroselinum crispum]
0.0 [2..383] [5..372]
NTF4_TOBAC - Mitogen-activated protein kinase homolog NTF4 OS=Nicotiana tabacum GN=NTF4 PE=2 SV=1
0.0 [2..385] [24..392]
gi|7649153 - gi|7649153|gb|AAF65766.1|AF242308_1 mitogen-activated protein kinase [Euphorbia esula]
0.0 [6..384] [24..387]
gi|30171839 - gi|30171839|gb|AAP20419.1| mitogen-activated protein kinase 1 [Lycopersicon esculentum]
0.0 [11..384] [36..394]
gi|21165523 - gi|21165523|dbj|BAB93529.1| mitogen-activated protein kinase [Solanum tuberosum]
0.0 [11..384] [36..394]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNCTLTDNTR AINVASNLGA PQQRTIFAKE RISIPGYYEI IQFLGKGAYG TVCSVKFKGR  60
   61 SPAARIAVKK ISNIFNKEIL LKRAIRELKF 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [103-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIDLEIVTSS PYDGLYCYQE L

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [358-388]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YESELNSMSK LRDYLVEEVK NFKTDLSSSS L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 803.9897
Match: 1erk__
Description: MAP kinase Erk2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [91-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFFKGHKNI VN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [124-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDYDLAKVIH SSVQLSEFHI KYFLYQILCG LKYIHSADVI HRDLKPGNIL CTLNGCLKIC  60
   61 DFGLARGIHA GFFKCHSTVQ PHITNYVATR WYRAPELLLS NQPYSKSVDI WAVGCILAEF 120
  121 YARKPVFMGR DSMHQIFEII KVLGTPDKDI LIKFGTIKAW NLGKNSNNPV YKKIPWSNIF 180
  181 PFASHEAINL IESLLHWDST HRLNVEQAIS HPFLNEVRKP DDEPVCLQGP FDFT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 803.9897
Match: 1erk__
Description: MAP kinase Erk2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle