YRC Public Data Repository - Protein Structure Prediction

Protein:	YPL275W
Organism:	Saccharomyces cerevisiae
Length:	236 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPL275W.

Description	E-value	Query Range	Subject Range
GYAR_THELI - Glyoxylate reductase OS=Thermococcus litoralis GN=gyaR PE=1 SV=1 GYAR_THELN - Glyoxylate reductase OS=Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) GN=g...	7.0E-76	[2..231]	[119..331]
SERA_RAT - D-3-phosphoglycerate dehydrogenase OS=Rattus norvegicus GN=Phgdh PE=1 SV=3	9.0E-76	[2..232]	[121..332]
PHGDH - phosphoglycerate dehydrogenase gi\|123982516, gi... - gi\|157928102\|gb\|ABW03347.1\| phosphoglycerate dehydrogenase [synthetic construct], gi\|123982516\|gb\|AB...	3.0E-75	[2..232]	[121..332]
gi\|7431368 - gi\|7431368\|pir\|\|H69229 phosphoglycerate dehydrogenase - Methanobacterium thermoautotrophicum (strain... SERA_METTH - D-3-phosphoglycerate dehydrogenase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DS...	5.0E-75	[2..232]	[117..328]
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1 SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...	6.0E-75	[2..233]	[115..328]
SERA_MOUSE - D-3-phosphoglycerate dehydrogenase OS=Mus musculus GN=Phgdh PE=1 SV=3	1.0E-74	[2..232]	[73..284]
gi\|22294046, gi\|... - gi\|22297868\|ref\|NP_681115.1\| D-3-phosphoglycerate dehydrogenase [Thermosynechococcus elongatus BP-1]...	2.0E-74	[2..234]	[115..330]
SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 /... SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus GN=serA PE=3 SV=1	1.0E-71	[2..224]	[115..317]

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Predicted Domain #1

Region A:
Residues: [1-186]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVINKQLMV SGILPAWLKN EYDLEDKIIS TVGAGRIGYR VLERLVAFNP KKLLYYDYQE  60
   61 LPAEAINRLN EASKLFNGRG DIVQRVEKLE DMVAQSDVVT INCPLHKDSR GLFNKKLISH 120
  121 MKDGAYLVNT ARGAICVAED VAEAVKSGKL AGYGGDVWDK QPAPKDHPWR TMDNKDHVGN 180
  181 AMTVHI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	484.927757
Match:	2nacA_
Description:	Formate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [187-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGTSLHAQKR YAQGVKNILN SYFSKKFDYR PQDIIVQNGS YATRAYGQKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	484.927757
Match:	2nacA_
Description:	Formate dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits