| Protein: | MDL2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 820 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDL2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [2..735] | [545..1276] |
|
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0.0 | [2..735] | [551..1282] |
|
|
0.0 | [2..735] | [539..1270] |
|
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0.0 | [2..735] | [367..1098] |
|
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0.0 | [2..735] | [535..1266] |
|
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0.0 | [17..735] | [577..1279] |
|
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0.0 | [2..735] | [543..1274] |
|
Region A: Residues: [1-134] |
1 11 21 31 41 51
| | | | | |
1 MKTYVLLYGK LIMTTMILNT GRFEEWYKVC IIALKEKEIY VPSSPIAMLN GRLPLLRLGI 60
61 CRNMLSRPRL AKLPSIRFRS LVTPSSSQLI PLSRLCLRSP AVGKSLILQS FRCNSSKTVP 120
121 ETSLPSASPI SKGS
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.362 | a.26.1 | 4-helical cytokines |
| View | Download | 0.450 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.297 | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.250 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.244 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
|
Region A: Residues: [135-257] |
1 11 21 31 41 51
| | | | | |
1 ARSAHAKEQS KTDDYKDIIR LFMLAKRDWK LLLTAILLLT ISCSIGMSIP KVIGIVLDTL 60
61 KTSSGSDFFD LKIPIFSLPL YEFLSFFTVA LLIGCAANFG RFILLRILSE RVVARLRANV 120
121 IKK
|
|
Region B: Residues: [276-473] |
1 11 21 31 41 51
| | | | | |
1 SRLGSDAYVV SRSMTQKVSD GVKALICGVV GVGMMCSLSP QLSILLLFFT PPVLFSASVF 60
61 GKQIRNTSKD LQEATGQLTR VAEEQLSGIK TVQSFVAEGN ELSRYNVAIR DIFQVGKTAA 120
121 FTNAKFFTTT SLLGDLSFLT VLAYGSYLVL QSQLSIGDLT AFMLYTEYTG NAVFGLSTFY 180
181 SEIMQGAGAA SRLFELTD
|
| Detection Method: | |
| Confidence: | 1660.0 |
| Match: | 1jsqA_ |
| Description: | MsbA |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [258-275] |
1 11 21 31 41 51
| | | | | |
1 TLHQDAEFFD NHKVGDLI
|
|
Region B: Residues: [474-752] |
1 11 21 31 41 51
| | | | | |
1 RKPSISPTVG HKYKPDRGVI EFKDVSFSYP TRPSVQIFKN LNFKIAPGSS VCIVGPSGRG 60
61 KSTIALLLLR YYNPTTGTIT IDNQDISKLN CKSLRRHIGI VQQEPVLMSG TIRDNITYGL 120
121 TYTPTKEEIR SVAKQCFCHN FITKFPNTYD TVIGPHGTLL SGGQKQRIAI ARALIKKPTI 180
181 LILDEATSAL DVESEGAINY TFGQLMKSKS MTIVSIAHRL STIRRSENVI VLGHDGSVVE 240
241 MGKFKELYAN PTSALSQLLN EKAAPGPSDQ QLQIEKVIE
|
| Detection Method: | |
| Confidence: | 1660.0 |
| Match: | 1jsqA_ |
| Description: | MsbA |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [753-820] |
1 11 21 31 41 51
| | | | | |
1 KEDLNESKEH DDQKKDDNDD NDNNHDNDSN NQSPETKDNN SDDIEKSVEH LLKDAAKEAN 60
61 PIKITPQP
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.441 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.446 | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.423 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.460 | d.52.5 | Probable GTPase Der, C-terminal domain |
| View | Download | 0.362 | d.58.23 | Probable ACP-binding domain of malonyl-CoA ACP transacylase |
| View | Download | 0.355 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.343 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.342 | d.45.1 | ClpS-like |
| View | Download | 0.327 | a.60.8 | HRDC-like |
| View | Download | 0.320 | g.50.1 | FYVE/PHD zinc finger |
| View | Download | 0.320 | a.64.1 | Saposin |
| View | Download | 0.283 | a.28.1 | ACP-like |
| View | Download | 0.281 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.281 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.278 | d.58.49 | YajQ-like |
| View | Download | 0.259 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.233 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.221 | d.45.1 | ClpS-like |
| View | Download | 0.210 | a.157.1 | Skp1 dimerisation domain-like |
| View | Download | 0.205 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.203 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.202 | a.4.5 | "Winged helix" DNA-binding domain |
