YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: DIM1
Organism: Saccharomyces cerevisiae
Length: 318 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIM1.

Description E-value Query
Range
Subject
Range
DIM1 - Essential 18S rRNA dimethylase (dimethyladenosine transferase), responsible for conserved m6(2)Am6(2...
gi|190407700 - gi|190407700|gb|EDV10965.1| dimethyladenosine transferase [Saccharomyces cerevisiae RM11-1a]
gi|151942536 - gi|151942536|gb|EDN60882.1| dimethyladenosine transferase [Saccharomyces cerevisiae YJM789]
DIM1_YEAST - Dimethyladenosine transferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DIM1 PE=3 ...
3.0E-83 [1..318] [1..318]
DIM1_MOUSE - Probable dimethyladenosine transferase OS=Mus musculus GN=Dimt1 PE=2 SV=1
7.0E-82 [1..318] [1..313]
DIMT1L - DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
gi|123995987, gi... - gi|123996331|gb|ABM85767.1| dimethyladenosine transferase [synthetic construct], gi|123995987|gb|ABM...
gi|114600097 - gi|114600097|ref|XP_517743.2| PREDICTED: dimethyladenosine transferase isoform 3 [Pan troglodytes]
4.0E-81 [1..318] [1..313]
DIM1_MACFA - Probable dimethyladenosine transferase OS=Macaca fascicularis GN=DIMT1 PE=2 SV=1
1.0E-80 [1..318] [1..313]
DIM1_KLULA - Dimethyladenosine transferase OS=Kluyveromyces lactis GN=DIM1 PE=3 SV=3
DIM1_KLULA - Dimethyladenosine transferase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBR...
2.0E-80 [1..318] [1..320]
DIM1A_ARATH - Ribosomal RNA small subunit methyltransferase OS=Arabidopsis thaliana GN=DIM1A PE=1 SV=1
1.0E-79 [2..318] [4..353]
gi|220954304, gi... - gi|220954304|gb|ACL89695.1| CG11837-PA [synthetic construct], gi|220944428|gb|ACL84757.1| CG11837-PA...
CG11837-PA - This gene is referred to in FlyBase by the symbol Dmel\CG11837 (CG11837, FBgn0039627). It is a prote...
gi|195574637, gi... - gi|195574637|ref|XP_002105291.1| GD21406 [Drosophila simulans], gi|194201218|gb|EDX14794.1| GD21406 ...
4.0E-79 [1..318] [1..306]
DIM1_SCHPO - Dimethyladenosine transferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dim1 PE=3 SV...
SPBC336.02 - 18S rRNA dimethylase
6.0E-79 [1..318] [1..307]
gi|23497221, gi|... - gi|23509377|ref|NP_702044.1| dimethyladenosine transferase, putative [Plasmodium falciparum 3D7], gi...
1.0E-78 [7..317] [49..352]
CE30642 - rRNA methyltransferase status:Confirmed UniProt:Q09522 protein_id:CAA87382.2
9.0E-76 [1..317] [1..306]

Back

Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKAAKKKYS GATSSKQVSA EKHLSSVFKF NTDLGQHILK NPLVAQGIVD KAQIRPSDVV  60
   61 LEVGPGTGNL TVRILEQAKN VVAVEMDPRM AAELTKRVRG TPVEKKLEIM LGDFMKTELP 120
  121 YFDICISNTP YQISSPLVFK LINQPRPPRV SILMFQREFA LRLLARPGDS LYCRLSANVQ 180
  181 MWANVTHIMK VGKNNFRPPP QVESSVVRLE IKNPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.9897
Match: 1yub__
Description: rRNA adenine dimethylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
rRNA methyltransferase activity 4.09362182773099 bayes_pls_golite062009
N-methyltransferase activity 4.00768472859991 bayes_pls_golite062009
methyltransferase activity 3.57681394097837 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.49392219433935 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
transferase activity 2.22303238506686 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 2.00108769169811 bayes_pls_golite062009
RNA binding 1.99752836873461 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 1.83964463328968 bayes_pls_golite062009
tRNA methyltransferase activity 1.76571145896453 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 1.75675289134467 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
protein methyltransferase activity 0.94499223839747 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
rRNA (uridine-2'-O-)-methyltransferase activity 0.90544396691236 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
binding 0.777596419415505 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.742142092552002 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
mRNA binding 0.0540207721800283 bayes_pls_golite062009
histone methyltransferase activity 0.0408000230099101 bayes_pls_golite062009
snoRNA binding 0.00848192089639488 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [216-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQVDYNEWDG LLRIVFVRKN RTISAGFKST TVMDILEKNY KTFLAMNNEM VDDTKGSMHD  60
   61 VVKEKIDTVL KETDLGDKRA GKCDQNDFLR LLYAFHQVGI HFS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.9897
Match: 1yub__
Description: rRNA adenine dimethylase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle